FWD 2 Botanical Adulterants Monitor


Dear Reader

The turmeric root/rhizome and root/rhizome extract Botanical Adulteration Bulletin (BAB), issued in May 2018, is the 14th in the series of bulletins published by the Botanical Adulterants Prevention Program (BAPP). Turmeric is one of the most important spices, and also among the most popular dietary supplement ingredients globally. The increased demand for turmeric extracts and the improvement of laboratory analytical test methods have led to new ways to adulterate the ingredient, such as the addition of synthetically-made curcumin or curcuminoid mixtures. The turmeric bulletin assists lab directors, quality control managers, and others in staying informed on these challenges in order to adjust the identity testing protocols in quality control laboratories.


  Stefan Gafner, PhD
Chief Science Officer, ABC
Technical Director, ABC-AHP-NCNPR Botanical Adulterants Program

ABC-AHP-NCNPR Botanical Adulterants Prevention Program

Recent News 

Turmeric Root/Rhizome and Extract Bulletin Published by the Program 

In May the ABC-AHP-NCNPR Botanical Adulterants Prevention Program released the Botanical Adulterants Bulletin (BAB) on turmeric adulteration. Turmeric (Curcuma longa, Zingiberaceae) dietary supplements have seen a steady increase in sales in the United States and other parts of the world.


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Botanical Adulterants Prevention Program Releases Boswellia Bulletin 

Dietary supplements made with extracts of the oleogum resin of boswellia (Boswellia serrata, Burseraceae), an important medicinal plant in the Ayurvedic medicine system in India, have shown one of the highest sales growth rates in the United States over the past five years. At the same time, reports have emerged that some products sold as Boswellia serrata extracts are actually made from other Boswellia resins, or from resins of altogether different genera of trees.


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ABC-AHP-NCNPR Botanical Adulterants Prevention Program Welcomes New Supporters and Underwriters 

The ABC-AHP-NCNPR Botanical Adulterants Prevention Program is grateful to the following companies that have recently committed to financially underwriting the Program:
  • Biotropics Malaysia
  • Designs for Health
  • Trust Transparency Center

The following trade associations have also joined as supporters of BAPP recently:

  • Global Curcumin Association (GCA)
  • Natural Astaxanthin Association (NAXA)

Regulatory Alerts

CSPI Calls for FDA Enforcement Action Against Adulterated Ginkgo Extract Products 

In a letter signed by Laura MacCleery, Director of Regulatory Affairs for the Center for Science in the Public Interest (CSPI), the consumer advocacy group requested the US FDA to act against the sale of adulterated ginkgo leaf extract products. 

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Industry Alerts

Evidence for Adulteration of Ginkgo Leaf Extracts from Europe 

Details of the investigation into the quality of 15 ginkgo leaf dietary supplements by the Sydney, Australia-based Network Nutrition-IMCD (summarized in the previous Botanical Adulterants Monitor) have now been published. The results from this evaluation of commercial mono-herbal formulations containing Ginkgo biloba leaf extracts, sourced from stores in Europe can be requested from the company (networknutrition@imcd.com.au) according to a press-release from May 7, 2018. 

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Upcoming Events

Below are descriptions and links to some of the upcoming conferences, seminars, and workshops that may be of interest to learn more on adulteration.

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Previous Issues of “Botanical Adulterants Monitor”

Available here.

Science Update

Isotopic Fingerprinting and NMR Analysis Detects Designer Blends Made with Animal Fats Marketed as Saw Palmetto Extracts

Perini M, Paolini M, Camin F, Appendino G, Vitulo F, De Combarieu E, Sardone N, Martinelli EM, Pace R. Combined use of isotopic fingerprint and metabolomics analysis for the authentication of saw palmetto (Serenoa repens) extracts. Fitoterapia.2018;127:15-19.


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HPTLC and UHPLC-MS Analysis of Commercial Cranberry Products

Reviewed: Boudesocque-Delaye L, Arnaud Lanoue A, Dorat J, Bruyère F, Gueiffier A, Enguehard-Gueiffier C. Quality control of commercial cranberry products: HPTLC-densitometry a new deal. Food Control. 2018;86:214-223.

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Analysis of Flavonoid and Terpene Lactone Contents in European Ginkgo Dietary Supplements Once Again Reveals Quality Issues and Adulteration

Reviewed: Czigle S, Tóth J, Jedlinszki N, Háznagy-Radnai E, Csupor D, Tekelová D. Ginkgo biloba food supplements on the European market – Adulteration patterns by quality control of selected samples. Planta Med. 2018;84(6-7):475-482. doi: 10.1055/a-0581-5203.


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HPTLC and DNA Metabarcoding Analysis of 53 Commercial Echinacea Dietary Supplement Products

Reviewed: Raclariu AC, Ţebrencu CE, Ichim MC, Ciupercǎ OT, Brysting AK, De Boer H. What's in the box? Authentication of Echinacea herbal products using DNA metabarcoding and HPTLC. Phytomedicine. 2018;44:32-38.


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A HPTLC Fingerprinting Method for the Authentication of Angelica gigas and Other Important Apiaceae Members

Reviewed: Frommenwiler DA, Kim J, Yook C-S, Tran TTT, Cañigueral S, Reich E. Comprehensive HPTLC fingerprinting for quality control of an herbal drug – the case of Angelica gigas root. Planta Med. 2018;84(6-7):465-474. doi: 10.1055/a-0575-4425.


Low-Field NMR as a Complementary Tool to Detect Patchouli Oil Adulteration

Reviewed: Krause A, Wu Y, Tian R, van Beek T. Is low-field NMR a complementary tool to GC‑MS in quality control of essential oils? A case study: Patchouli essential oil. Planta Med. 2018; Apr 24. doi: 10.1055/a-0605-3967. [Epub ahead of print]




Useful Links and Resources

For more information and updates on the work of the three partner organizations of the ABC-AHP-NCNPR Botanical Adulterants Program, please visit ABC at www.herbalgram.org, AHP at www.herbal-ahp.org, and NCNPR at www.pharmacy.olemiss.edu/ncnpr.

Other Helpful Resources and Links

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About the

The ABC-AHP-NCNPR Botanical Adulterants Program is a consortium of independent nonprofit organizations whose mission relates to education, scientific research, and quality of botanical dietary ingredients and related plant-derived materials. The consortium is headed by three nonprofit groups dealing with education and research on medicinal herbs and other beneficial plants: the American Botanical Council, the American Herbal Pharmacopoeia, and the National Center for Natural Products Research at the University of Mississippi. The program is underwritten or endorsed by more than 130 natural products industry companies, independent analytical laboratories, contract research organizations, nonprofit and professional organizations, trade associations, accredited institutions of education in natural medicine, law firms, and media companies that are involved in the production, supply, manufacture, distribution, marketing, analysis, research, and/or education of herbal dietary ingredients and supplements, in the United States and internationally. All publications of the Program are available free-access on its homepage including the “Botanical Adulterants Monitor,” an e-newsletter that conveys Program news, regulatory updates, and recent scientific publications related to adulteration, contamination, identity, and authenticity of botanical raw materials, extracts, and essential oils. Companies, organizations, foundations, and/or individuals interested in supporting this program are invited to contact Ms. Denise Meikel, ABC Development Director, at (512) 926-4900, ext. 120, or by email.


Thank You to Our Supporters

Underwriters and Supporters of the ABC-AHP-NCNPR Botanical Adulterants Program (as of August 3, 2018)*

*By acknowledging the generous support of these companies and organizations, ABC, AHP, and NCNPR are not endorsing any ingredients or products that may be produced or marketed by them.

Financial Underwriters

221st Century Healthcare
AdvoCare International L.P.
Agilent Technologies, Inc.
Aloecorp, Inc.
Amen Clinics
Amway/Nutrilite Health Institute
Arbonne International
Arizona Nutritional Supplements
Artemis International, Inc.
Atrium Innovations
Aveda Corporation
Beachbody, LLC
BI Nutraceuticals
Bionorica SE
Biotropics Malaysia
Botanical Liaisons
Bruker BioSpin
Cepham, Inc.
Chemi Nutra
CNCA Health
Complete Phytochemical Solutions
Crila Health
Designs for Health
dicentra, Inc.
Doctor’s Best
Dr. Bronner's Magic Soaps
DolCas Biotech, LLC
dōTERRA International, LLC
Douglas Laboratories
Draco Natural Products
Emerson Ecologics
Enzymatic Therapy, Inc.
Ethical Naturals, Inc.
Eu Yan Sang International
Flavex Naturextrakte GmbH
Fruit d’Or
Gaia Herbs
GE Nutrients, Inc.
Ginsana SA
Global Health Industries
GNC, Inc.
Healthy Lifestyle Brands, LLC
Helios Corp.
Herb Pharm
Herbalife International, Inc.
Horphag Research
Indena USA, Inc.
Indfrag Limited
Ingredient Identity
Ixoreal Biomed Inc.
Jarrow Formulas
Klaire Labs
Layn USA, Inc.
Markan Global Enterprises, Inc.
Martin Bauer, Inc.
MediHerb / Integria Healthcare
Metagenics, Inc.

Financial Underwriters

Natreon, Inc.
Natural Alternatives International, Inc.
Natural Factors Nutritional Products, Inc./Bioclinic Naturals
Natural Grocers by Vitamin Cottage
Natural Partners, Inc.
Natural Remedies Pvt. Ltd.
Nature's Sunshine Products
Nature's Way
Naturex, Inc.
NBTY, Inc.
Network Nutrition – IMCD
New Chapter, Inc.
The New Frontier Foundation Fund of the Greater Cedar Rapids Community Foundation
Ningbo Greenhealth Pharmaceutical Co., Ltd.
Novel Ingredients
NOW Health Group
Nu Skin Enterprises/Pharmanex
Nutraceutical Corp
OmniActive Health Technologies, Inc.
Organic India
Ortho Molecular Products
Pacific Nutritional Inc.
Paragon Laboratories
Pathway International Pty Limited
Perrigo Company
Pharmatoka SAS
Pharmavite, LLC
Phoenix Formulations
PLT Health Solutions, Inc.
Polyphenolics, Division of Constellation Brands, Inc.
Pure Encapsulations
Rainbow Light Nutritional Systems
RFI Ingredients, LLC
Rosenbush and Zimmerman Family Fund
Sabinsa Corporation
Schwabe North America
SFI Research
Shaklee Corp.
Soho Flordis International
SOHO Global Health
Standard Process, Inc.
Strategic Sourcing, Inc.
Thorne Research, Inc.
Tishcon Corp.
Traditional Medicinals, Inc.
Trust Transparency Center
TSI Group
Univera, Inc.
Valensa International
V.D.F. FutureCeuticals
Verdure Sciences
Vitamin Shoppe
VitaQuest International
Whole Foods Market

Trade Associations

American Herbal Products Association (US)
Australian Self Medication Industry (Australia)
Australian Tea Tree Industry Association (Australia)
British Herbal Medicine Association (UK)
Canadian Health Food Association (Canada)
Complementary Medicines Australia (Australia)
Consumer Healthcare Products Association (US)
Council for Responsible Nutrition (US)
Global Curcumin Association (GCA)
International Alliance of Dietary/Food Supplement Associations (IADSA)
National Animal Supplement Council (US)
Natural Astaxanthin Association (NAXA)
Natural Products Association (US)
Natural Products New Zealand (NZ)
United Natural Products Alliance (US)

Nonprofit/Professional Associations

Academy of Integrative Health & Medicine
American Association of Naturopathic Physicians
American Herbalists Guild
American Society of Pharmacognosy
AOAC International
Council of Colleges of Acupuncture and Oriental Medicine
Homeopathic Pharmacopoeia Convention of the United States
Integrative Healthcare Policy Consortium
Irish Register of Herbalists (IRE)
National Institute of Medical Herbalists (UK)
Natural Health Products Research Society of Canada (NHPRS Canada)
Personalized Lifestyle Medicine Institute
Society for Medicinal Plant and Natural Product Research (GA)


Bastyr University
Boucher Institute for Naturopathic Medicine
Center for Natural Products Technologies, College of Pharmacy, University of Illinois-Chicago
Hong Kong Baptist University’s School of Chinese Medicine
Maryland University of Integrative Health
National College of Natural Medicine
Southwest College of Naturopathic Medicine
University of Bridgeport College of Naturopathic Medicine
Third-Party Analytical Laboratories

Alkemist Labs
NSF AuthenTechnologies
Bent Creek Institute
BotaniCert (France)
British Columbia Institute of Technology
Creative Accord, LLC
Eurofins Scientific Inc.
Flora Research Labs
NSF International
PhytoLab (Germany)
Spectrix Labs
Tampa Bay Analytical


Alive Publishing Group
Delicious Living
Holistic Primary Care
IMPACT Health Media, Inc.
Informa Exhibitions US
Integrator Blog
Media Relations, Inc.
Modern Healthcare Practitioner
Natural Foods Merchandiser
Natural Medicine Journal
Natural Products INSIDER
Nutraceuticals World
Nutrition Business Journal
Nutrition Industry Executive
Nutritional Outlook
Vitamin Retailer
WholeFoods Magazine


Law Firms & Regulatory Consultants

AAmin Talati & Upadhye, LLC
Greenberg Traurig, LLP (James Prochnow)
Law Office of Holly Bayne, P.C.
Robert Forbes & Associates
Susan Brienza, LLC
Ullman, Shapiro & Ullman, LLP

Contract Research Organizations

KGK Synergize


Research Institutes

Korean Ginseng Research Institute
Shanghai Research Center for TCM Modernization/Shanghai Institute of Materia Medica of the Chinese Academy of Sciences


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