Dear Reader

The Botanical Adulterants Prevention Program (BAPP) has released four more peer-reviewed publications between September and November 2018. The Maca Botanical Adulterants Prevention Bulletin and the Tea Tree Oil Laboratory Guidance Document (LGD) were published in September, followed by a revised bulletin on saw palmetto berries and berry extracts in October, and the LGD on cranberry, which was issued in November.

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Stefan Gafner, PhD
Chief Science Officer, ABC
Technical Director, ABC-AHP-NCNPR Botanical Adulterants Program

ABC-AHP-NCNPR Botanical Adulterants Program

Recent News

Botanical Adulterants Prevention Bulletin on Maca Published by BAPP

The ABC-AHP-NCNPR Botanical Adulterants Prevention Program released the 16th in the series of Botanical Adulterants Prevention Bulletins (BAPB) on maca adulteration. Maca (Lepidium meyenii, syn. L. peruvianum, Brassicaceae) hypocotyls have been cultivated in the Peruvian Andes for thousands of years as a nutritious food, and have a history of use as medicine to enhance fertility, to provide more energy, and for its effect on mood and well-being.

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Botanical Adulterants Prevention Program Releases Tea Tree Oil Laboratory Guidance Document

In September, the Laboratory Guidance Document (LGD) on methods to authenticate and detect adulteration of the essential oil made from the leaves of tea tree (Melaleuca alternifolia and M. linariifolia, Myrtaceae) was published.

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Revised Saw Palmetto Bulletin Documents Adulteration with Fatty Acids from Animal Sources

Adulteration of saw palmetto (Serenoa repens, Arecaceae) by adding undeclared vegetable oils, e.g., palm oil, canola oil, coconut oil, or sunflower oil, to saw palmetto extracts for financial gain has been known since in the early 2000s..

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Most Recent in Series of Laboratory Guidance Documents Evaluates Methods to Authenticate Cranberry Products

Cranberry dietary supplements are widely used for the prevention and adjuvant treatment of recurrent urinary tract infections. There are important differences in the composition of the various cranberry supplements on the market.

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ABC-AHP-NCNPR Botanical Adulterants Prevention Program Welcomes New Supporters and Underwriters

The ABC-AHP-NCNPR Botanical Adulterants Prevention Program is grateful to the following companies that have recently committed to financially underwriting the Program:

Bio-Botanica
Nature's Answer
Taiyo
Tomorrow’s Nutrition
Regular Girl

Upcoming Events

Below are descriptions and links to some of the upcoming conferences, seminars, and workshops that may be of interest to learn more on adulteration.

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Previous Issues of “Botanical Adulterants Monitor”

Available here.

Science Update

HPLC-FD Determination of Catechin, Epicatechin, and Procyanidins A2 and B2 for the Classification of Cranberry Products Sold in Europe

Reviewed: Bakhytkyzy I, Nuñez O, Saurina J. Determination of flavanols by liquid chromatography with fluorescence detection. Application to the characterization of cranberry-based pharmaceuticals through profiling and fingerprinting approaches. J Pharm Biomed Anal. 2018;156:206-213.

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FT-NIR Combined with Chemometric Analysis as a Means to Distinguish Powdered Goldenseal Root from its Adulterants

Reviewed: Liu Y, Finley J, Betz JM, Brown PN. FT-NIR characterization with chemometric analyses to differentiate goldenseal from common adulterants. Fitoterapia. 2018;127:81-88.

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Crowdsourcing to Support High School Project on DNA Authentication of 32 Herbal Dietary Supplements

Reviewed: Molina J, Sherpa C, Ng J, Sonam T, Stuhr N. DNA barcoding of online herbal supplements: crowd-sourcing pharmacovigilance in high school. Open Life Sci. 2018;13:48-55.

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Detection of Japanese Sophora in Commercial Ginkgo Leaf Products Using Species-Specific DNA Sequences

Reviewed: Liu Y, Wang XY, Wei XM, Gao ZT, Han JP. Rapid authentication of Ginkgo biloba herbal products using the recombinase polymerase amplification assay. Sci Rep. 2018;8(1):8002.

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Characterization of Four Commercial Grape Seed Extracts Using UHPLC-UV/CAD/HRMS, GC-FID, and GC-MS

Reviewed: Sica VP, Mahoney C, Baker TR. Multi-detector characterization of grape seed extract to enable in silico safety assessment. Front Chemistry. 2018;6:334. doi: 10.3389/fchem.2018.00334.

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Useful Links and Resources

For more information and updates on the work of the three partner organizations of the ABC-AHP-NCNPR Botanical Adulterants Program, please visit ABC at www.herbalgram.org, AHP at www.herbal-ahp.org, and NCNPR at www.pharmacy.olemiss.edu/ncnpr.

Other Helpful Resources and Links

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About the

The ABC-AHP-NCNPR Botanical Adulterants Program is a consortium of independent nonprofit organizations whose mission relates to education, scientific research, and quality of botanical dietary ingredients and related plant-derived materials. The consortium is headed by three nonprofit groups dealing with education and research on medicinal herbs and other beneficial plants: the American Botanical Council, the American Herbal Pharmacopoeia, and the National Center for Natural Products Research at the University of Mississippi. The program is underwritten or endorsed by more than 130 natural products industry companies, independent analytical laboratories, contract research organizations, nonprofit and professional organizations, trade associations, accredited institutions of education in natural medicine, law firms, and media companies that are involved in the production, supply, manufacture, distribution, marketing, analysis, research, and/or education of herbal dietary ingredients and supplements, in the United States and internationally. All publications of the Program are available free-access on its homepage including the “Botanical Adulterants Monitor,” an e-newsletter that conveys Program news, regulatory updates, and recent scientific publications related to adulteration, contamination, identity, and authenticity of botanical raw materials, extracts, and essential oils. Companies, organizations, foundations, and/or individuals interested in supporting this program are invited to contact Ms. Denise Meikel, ABC Development Director, at (512) 926-4900, ext. 120, or by email.

Thank You to Our Supporters

Underwriters and Supporters of the ABC-AHP-NCNPR Botanical Adulterants Program (as of December 9, 2018)*

*By acknowledging the generous support of these companies and organizations, ABC, AHP, and NCNPR are not endorsing any ingredients or products that may be produced or marketed by them.

Financial Underwriters

21st Century Healthcare

AdvoCare International L.P.

Agilent Technologies, Inc.

Aloecorp, Inc.

Amen Clinics

Amway/Nutrilite Health Institute

Arbonne International

Arizona Nutritional Supplements

Artemis International, Inc.

Atrium Innovations

Aveda Corporation

Beachbody, LLC

BI Nutraceuticals

Bioceuticals

Bionorica SE

Bio-Botanica

Blackmores

Botanical Liaisons

Bruker BioSpin

Capsugel

Cepham, Inc.

Chemi Nutra

CNCA Health

Complete Phytochemical Solutions

Crila Health

dicentra, Inc.

Doctor’s Best

Dr. Bronner's Magic Soaps

DolCas Biotech, LLC

Douglas Laboratories

Draco Natural Products

Emerson Ecologics

Enzymatic Therapy, Inc.

Ethical Naturals, Inc.

Eu Yan Sang International

EuroMed

EuroMedica

EuroPharma

Flavex Naturextrakte GmbH

FoodState/MegaFood

Fruit d'Or

Gaia Herbs

GE Nutrients, Inc.

Global Health Industries

GNC, Inc.

Healthy Lifestyle Brands, LLC

Helios Corp.

Herb Pharm

Herbalife International, Inc.

Horphag Research

iHerb

Indena USA, Inc.

Indfrag Limited

Ingredient Identity

Ixoreal Biomed, Inc.

Jarrow Formulas

Layn USA, Inc.

Linnea

Markan Global Enterprises, Inc.

Martin Bauer, Inc.

MediHerb / Integria Healthcare

Financial Underwriters
(cont'd)

Metagenics, Inc.

Natreon, Inc.

Natrol

Natural Alternatives International, Inc.

Natural Factors Nutritional Products, Inc.
/Bioclinic Naturals

Natural Grocers by Vitamin Cottage

Natural Remedies Pvt. Ltd.

Nature's Answer

Nature's Sunshine Products

Nature's Way

Naturetech

Naturex, Inc.

NBTY, Inc.

New Chapter, Inc.

The New Frontier Foundation Fund of the Greater Cedar Rapids Community Foundation

Ningbo Greenhealth Pharmaceutical Co., Ltd.

Novel Ingredients

NOW Foods

Nu Skin Enterprises/Pharmanex

Nutraceuticals Corp.

Organic India

Ortho Molecular Products

Pacific Nutritional Inc.

Paragon Laboratories

Pathway International Pty Limited

Perrigo Company

Pharmatoka SAS

Pharmavite, LLC

Phoenix Formulations

PLT Health Solutions, Inc.

Polyphenolics, Division of Constellation Brands, Inc.

Pure Encapsulations

Rainbow Light Nutritional Systems

Regular Girl

RFI Ingredients, LLC

Rosenbush and Zimmerman Family Fund

Sabinsa Corporation

Schwabe North America

Seroyal

SFI Flordis

Shaklee Corp.

Standard Process, Inc.

Strategic Sourcing, Inc.

Taiyo

Thorne Research, Inc.

Tishcon Corp.

Tomorrow's Nutrition

Traditional Medicinals, Inc.

TSI Group

Unigen

Univera, Inc.

Valensa International

V.D.F. FutureCeuticals

Verdure Sciences

Vitamin Shoppe

VitaQuest International

Whole Foods Market

ZMC-USA

Trade Associations

American Herbal Products Association (US)

Australian Self Medication Industry (Australia)

Australian Tea Tree Industry Association (Australia)

British Herbal Medicine Association (UK)

Canadian Health Food Association (Canada)

Complementary Medicines Australia (Australia)

Consumer Healthcare Products Association (US)

Council for Responsible Nutrition (US)

International Alliance of Dietary/Food Supplement Associations (IADSA)

National Animal Supplement Council (US)

Natural Products Association (US)

Natural Products New Zealand (NZ)

United Natural Products Alliance (US)

Nonprofit/Professional Associations

Academy of Integrative Health & Medicine

American Association of Naturopathic Physicians

American Herbalists Guild

American Society of Pharmacognosy

AOAC International

Council of Colleges of Acupuncture and Oriental Medicine

Homeopathic Pharmacopoeia Convention of the United States
Integrative Healthcare Policy Consortium

Irish Register of Herbalists (IRE)

National Institute of Medical Herbalists (UK)

Natural Health Products Research Society of Canada (NHPRS Canada)

Personalized Lifestyle Medicine Institute

Society for Medicinal Plant and Natural Product Research (GA)

Colleges/Universities

Bastyr University

Boucher Institute for Naturopathic Medicine

Center for Natural Products Technologies, College of Pharmacy, University of Illinois-Chicago

Hong Kong Baptist University’s School of Chinese Medicine

National College of Natural Medicine

Southwest College of Naturopathic Medicine

University of Bridgeport College of Naturopathic Medicine

Third-Party Analytical Laboratories

Alkemist Labs

AuthenTechnologies LLC

Bent Creek Institute

BotaniCert (France)

British Columbia Institute of Technology

ChromaDex

Covance Laboratories

Creative Accord, LLC

Eurofins Scientific Inc.

Flora Research Labs

NSF International

PhytoLab (Germany)

Spectrix Labs

Tampa Bay Analytical

Media

Alive Publishing Group

Delicious Living

Engredea

Holistic Primary Care

Informa Exhibitions US

Integrator Blog

Media Relations, Inc.

Modern Healthcare Practitioner

Natural Foods Merchandiser

Natural Medicine Journal

Natural Products INSIDER

Newhope360.com

Nutraceuticals World

NutraingredientsUSA.com

Nutrition Business Journal

Nutrition Industry Executive

Nutritional Outlook

Vitamin Retailer

WholeFoods Magazine

Law Firms & Regulatory Consultants

Amin Talati & Upadhye, LLC

Greenberg Traurig, LLP (James Prochnow)

Law Office of Holly Bayne, P.C.

Robert Forbes & Associates

Susan Brienza, LLC

Ullman, Shapiro & Ullman, LLP

Contract Research Organizations

KGK Synergize

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