FWD 2 Botanical Adulterants Monitor


Dear Reader,

Two new Botanical Adulterants Bulletins (BABs) on tea tree oil and rhodiola have been published as part of the ABC-AHP-NCNPR Botanical Adulterants Program. The BAB on tea tree oil, written by Ezra Bejar, PhD, details authenticity issues with this essential oil widely used for its antimicrobial and anti-inflammatory properties. The bulletin on adulteration of Rhodiola rosea, co-authored by Ezra Bejar, PhD, John Cardellina, PhD, and Roy Upton, documents some of the quality issues found with the authenticity of commercial products labeled to contain R. rosea. Differences in understanding of the meaning of rhodiola between Western manufacturers and Chinese traders, who use the common name hong jing tian as an umbrella term for a number of Rhodiola species, have led to a situation where a several Rhodiola species are commercially available labeled as R. rosea.

The fallout from the investigation into the authenticity of dietary supplements initiated by the New York Attorney General Eric Schneiderman has seen another chapter come to an end. In the weeks and months following the NY AG’s actions, a number of plaintiff’s attorneys filed class-action lawsuits against the four retailers, GNC, Target, Walgreen’s, and Walmart. These lawsuits were consolidated into one case, handled by the US District Court for Northern Illinois. In a move much less publicized than the initial NY AG actions, the three remaining defendants Target, Walgreen’s, and Walmart, have agreed to settle the dispute on July 11, 2017. Charges against the fourth retailer, GNC, were dismissed after the company entered an agreement with the NY AG. More details on the settlement are provided in the Regulatory Alerts section of this issue of the Botanical Adulterants Monitor.

Five papers have been summarized in the science section; two publications detail quality issues with sea buckthorn. Hurkova et al. report the adulteration of a commercial sea buckthorn oil supplement with sunflower oil, and Liu et al. present the findings of the identity determination of 10 samples of whole dried sea buckthorn berries sold in markets in China. Results of this analysis show that five samples contained berries from Amur mountain ash, barberry, or species of Nitraria, respectively, instead of sea buckthorn. A fairly comprehensive analysis of reishi supplements sold in the United States by chemical analysis concludes that only 26.3% of the products were compliant with label claims. This collaboration between the University of Macau and the United States Pharmacopeia found that a majority of the products contained predominantly starch, showing the need for improved quality control methods for such products. The paper by van der Valk et al. on macroscopic analysis of fruits and seeds of plants used in traditional Chinese medicine shows the extent of information that can be obtained by careful visual inspection of whole plant parts. Of the 211 samples analyzed, 9.5% did not contain the labeled species, while another 8.1% showed various degrees of adulteration. The last paper in this section, authored by researchers from the US Department of Agriculture, looked at the usefulness of feruloyl dopamine-O-hexosides as chemical marker compounds to distinguish among black cohosh and adulterating Actaea species.

This issue of the Botanical Adulterants Monitor also contains summaries of two presentations given at the 65th Annual meeting of the Society for Medicinal Plant and Natural Products Research (GA) in Basel, Switzerland. These presentations detail new methods to detect adulteration of ginkgo and St. John’s wort extracts.

We hope that the information included in this issue of the Botanical Adulterants Monitor will be useful. Feel free to circulate the information among your colleagues with the goal that the information will help to avoid adulterated ingredients’ finding their way into the supply chain for herbal dietary supplements and other finished botanical products.

Stefan Gafner, PhD
Chief Science Officer
American Botanical Council

Technical Director, ABC-AHP-NCNPR Botanical Adulterants Program