Issue: 63 Page: 26-31
Tamanu Oil: A Tropical Topical Remedy
by Chris Kilham
HerbalGram. 2004; 63:26-31 American Botanical Council
Many remedies sold today in the markets of developed nations
contain ingredients that have a long history of use by indigenous peoples in their
countries of origin. Such is the case with tamanu oil (Calophyllum inophyllum
L., Guttiferae), a traditional remedy with a history of native use in Polynesia
and Southeast Asia.1-4 Only within the past few years has tamanu oil
begun to penetrate the European and U.S. markets, primarily in the cosmetic sectors.
Since the 1930s the effectiveness of tamanu oil has been studied in hospitals
and by researchers in Europe, Asia, and the Pacific islands.2,5 This
research has revealed that tamanu oil is a significant topical healing agent with
skin healing,2,5,6 antineuralgic,2,5 anti-inflammatory,2,7-11
antimicrobial,2,12-14 and antioxidant13 properties.
Tamanu and Its Dispersal
The name of the genus Calophyllum means “beautiful leaf,” from the Greek kalos (beautiful) and phullon (leaf). The tree is indigenous to Southeast Asia,
and it is found in Thailand, Vietnam, Myanmar, Malaysia, South India, Sri
Lanka, and throughout the numerous islands of Melanesia and Polynesia.1-3,15
In the Society Islands this species is known by the names tamanu and ti.
In Hawaii it is known as kamanu
or kamani; in Samoa fetau; and in Fiji dolno (meaning “no pain”) or dilo.1,2 Tamanu grows up to 25 or even 30
meters in height, with long, spreading limbs. The tree trunk is typically thick
with dark, grayish-brown cracked bark. The branches are covered with shiny,
dark-green oval leaves, and small white flowers with yellow centers. The
blossoms give off a delightful, sweet perfume. The inedible mature green fruit
of the tree, about the size of an apricot, has a thin flesh and a large nut
hull inside.2,4,16
Though the tree can be successfully grown inland, tamanu
naturally occurs abundantly along coastal areas. The nut-containing fruits
disperse throughout the Pacific islands by dropping from the trees and floating
on the seas to other coastal areas where they sprout and root.17
Tamanu is unusual in that, unlike most other trees, it favors salty, sandy
soil.
Indigenous Polynesians interviewed by the author claim that
the oil from coastal tamanu trees is more beneficial for topical and cosmetic
uses than oil from inland trees. To date no studies have been conducted to
compare the oil from coastal and inland populations. Nonetheless, at this time
tamanu oil processors tend to favor the use of nuts from coastal trees, due
primarily to the ease of collecting nuts on sandy coastal areas.
Oil in Tamanu Nuts
When the fruits of the C. inophyllum tree are collected and cracked open, the blonde nut
kernel inside contains little evident oil upon pressing or grinding. But when
the kernel is dried on a rack for a month or so, it turns a deep, chocolate
brown, and becomes sticky with a rich oil. Once this transformation has taken
place, the oil can be easily extracted from the dark kernels using only
mechanical pressing. The resulting tamanu oil has a rich texture and
greenish-amber color. The means by which the tamanu kernel becomes oily remains
unknown. At present, no studies explain this process.
Tamanu Oil and Cicatrization
Tamanu oil applied to wounds possesses the capacity to
promote the formation of new tissue, thereby accelerating healing and the
growth of healthy skin. This process of forming new tissue is known as
cicatrization.2,6 Tamanu oil is a widely used traditional topical
aid. In Pacific island folk medicine, tamanu oil is applied liberally to cuts,
scrapes, burns, insect bites and stings, abrasions, acne and acne scars,
psoriasis, diabetic sores, anal fissures, sunburn, dry or scaly skin, blisters,
eczema, and herpes sores, and to reduce foot and body odor. Tamanu oil
reputedly relieves sore throat when it is applied topically to the neck. The
oil also demonstrates pain-relieving properties and has been used traditionally
to relieve neuralgia, rheumatism, and sciatica. Polynesian women apply tamanu
oil topically to promote healthy, clear, blemish-free skin, and massage it onto
babies to prevent diaper rash and skin eruptions.2,6,18
Anti-neuralgic
and Skin Healing Activity
Traditionally tamanu oil has a history of topical use for
relieving the pain of sciatica, shingles, neuralgia, rheumatism, and leprous
neuritis.5 In the late 1920s, Sister Marie-Suzanne, a nun in the
Society of Mary stationed in Fiji, became aware of a local topical aid for
neuritis known locally as dolno, i.e.,
tamanu oil. The nun began to administer tamanu oil topically to leprosy victims
for the relief of neuritis associated with that disease, with apparent positive
results. Her reports of success with this treatment attracted the interest of
scientists in France.2,5
As a result of its effective use in Fiji, tamanu oil was further investigated
by French researchers in the 1930s for its anti-neuralgic effects. But they quickly
became more interested in tamanu’s cicatrizing properties, which subsequently
received the most attention. French medical literature on tamanu oil reports several
instances of its successful use in cases of severe skin conditions, with photographs
showing before and after use.2,19 In one of the most remarkable instances,
a woman was admitted to the St. Louis Hospital in Paris with a large gangrenous
ulcer on her leg that would not heal. Though doctors were sure that amputation
was inevitable, she was given regular dressings of tamanu oil. The wound eventually
healed completely, leaving a smooth, flat scar.2 In other cases, tamanu
oil has been reportedly employed successfully to heal severe burns caused by boiling
water, chemicals, and X-rays.2,19
Lipid Composition of Tamanu Oil
The oil of tamanu contains basic classes of lipids (fats), enumerated
below.
General lipid composition |
|
Neutral lipids |
92% |
Glycolipids |
6.4% |
Phospholipids |
1.6% |
Neutral lipids |
|
Monoacylglycerols |
1.8% |
sn -1,3 – Diaglycerides |
2.4% |
sn -1,2 (2,3) – Diaglycerides |
2.6% |
Free fatty acids |
7.4% |
Triacylglycerols |
82.3% |
Sterols, sterolesters and hydrocarbons |
3.5% |
Glycolipids |
|
Monogalactosyldiacylglycerol |
11.4% |
Acylated sterolglucoside |
13.1% |
Monogalactosylmonoacylglycerol |
22.2% |
Acylmonogalactosyldiacylglycerol |
53.3% |
Phospholipids |
|
Phosphatidylethanolamine |
46.3% |
Phosphatidylcholine |
33.8% |
Phosphatidic acid |
8.1% |
Phosphatidylserine |
6.1% |
Lysophosphatidylcholine |
5.7% |
Source: References 2, 15, 22
Anti-inflammatory
Activity of Tamanu Oil
Tamanu oil demonstrates anti-inflammatory activity. This
activity is due partly to the 4-phenyl coumarin calophyllolide8,11,20
and to a group of xanthones in the oil, including dehydrocycloguanandin,
calophyllin-B, jacareubin, mesuaxanthone-A, mesuaxanthone-B, and euxanthone.
All the xanthones in tamanu oil show anti-inflammatory activity,10
which explains reductions of rashes, sores, swelling, and abrasions with
topical application of the oil.2
Antibacterial and Antifungal Activity of Tamanu Oil
Tamanu oil demonstrates significant antimicrobial activity,
as demonstrated in antibacterial and antifungal tests.2,13,14 The
oil contains several powerful bactericide/fungicide agents, which demonstrate
efficacy against various human and animal pathogens. These antimicrobial
phytochemical agents include friedelin, canophyllol, canophyllic acid, and
inophynone.13
In antibacterial studies conducted in Karachi, Pakistan,
researchers discovered the following:
Canophyllic acid demonstrated moderate antibacterial
activity, compared with ampicillin and amoxicillin, against Proteus
mirabilis (a cause of bladder infections, wound infections, septicemia,
and pneumonias, mostly in hospitalized patients).21
Canophyllol demonstrated good activity, compared with
ampicillin and amoxicillin, against Staphylococcus aureus (a cause of inflammation, suppuration, abscesses,
boils, infected wounds, septicemia, and conjunctivitis), Cornebacterium diptheriae (the cause of diphtheria), Klebsiella pneumonia (a cause of septicemia, infected wounds, and
infected burns), and Proteus mirabilis (a cause of urinary tract infection, septicemia, and infected wounds).21
Friedelin demonstrated good activity, compared with
ampicillin and amoxicillin, against S. aureus. In antifungal tests, the same researchers discovered the following:
Friedelin exhibited good antifungal activity against Pseudallescheria
boydii, (a cause of fungal keratitis and
Madura Foot, a disease in which the foot swells and suppurates, with multiple
open sinuses).21
Friedelin exhibited moderate activity against Trichophyton
schoenleinii (cutaneous fungus occurring in
hair, skin and nails, and associated with “jock itch,” ringworm, athlete’s
foot, and dermaphytosis of the scalp and beard).21
The n-butanol fraction of tamanu oil was examined against
various fungal cultures, showing significant activity against Trichophyton
semii and T. metagrophyte (both cutaneous fungi occurring in hair, skin and
nails, and associated with “jock itch,” ringworm, athlete’s foot, and
dermaphytosis, a fungal disease usually transmitted from animals to humans in
the scalp and beard).21
Researchers concluded that the antimicrobial agents in
tamanu oil could be used effectively to treat a range of infections of the skin
and eyes and to treat ringworm.13
Antioxidant Activity of Tamanu Oil
Xanthones and coumarins
in tamanu oil demonstrate antioxidant properties, specifically inhibiting lipid
peroxidation. Cell membranes are made of lipids. Lipids are organic compounds
that are oily to the touch and are insoluble in water but are soluble in
nonpolar organic solvents (e.g., chloroform, ether). Lipids include fats, oils,
waxes, sterols, and triglycerides. The antioxidant activity of tamanu oil helps
to protect skin cells from damage by reactive oxygen species (ROS) and other
oxidative antagonists.13
Current Tamanu Oil Popularity
Though investigations into tamanu oil have been conducted
continuously since the 1930s, only in the last decade has tamanu oil gained any
market visibility for general first aid and cosmetic use. Throughout the 1990s
much of this market activity was confined to Tahiti, where the pure oil is
marketed in bottles for first aid and beauty purposes. In Europe general market
interest in tamanu is relatively new, and cosmetic companies are currently
marketing products containing this oil. In the U.S. bottled tamanu oil is now
also marketed in pure and dilute forms, and it appears as an ingredient in a
limited number of cosmetic products.
Tamanu for Topical First Aid
Due to its cicatrizing, anti-inflammatory, and antimicrobial
activities, oil of tamanu is a versatile topical aid suitable for use in a
broad range of skin conditions. Oil of tamanu can be applied undiluted directly
to skin. There are no reports of adverse effects due to such application of
tamanu.
Tamanu for Cosmetics
Oil of tamanu is suitable for general skin and cosmetic
purposes. The oil’s mild and pleasant aroma and luxurious feel make it ideal
for use in lotions, creams, ointments, and other cosmetic products. Oil of
tamanu absorbs readily, leaving the skin feeling smooth and soft. The oil adds
a glow to skin, without any residual greasiness or oiliness. Tamanu oil has the
potential to be a significant ingredient for companies wanting to develop
beneficial natural products.
Tamanu Oil and Sustainable Harvesting
In indigenous communities, nut-containing tamanu fruits are
collected from the ground after they have dropped from the tree. Because the
fruits are collected after they drop, no negative impact upon the life or
ecology of the tamanu trees is caused by the harvest of the fruits. The trees
themselves are neither touched nor harmed. Habitat is not negatively impacted,
as neither the land nor any surrounding plants are disturbed as a result of
collection. If not collected, the fruits and nuts simply decompose. Thus,
tamanu collection is a low impact, environmentally sustainable activity.
In the Republic of Vanuatu, South Pacific, harvesting of
tamanu fruits from beach areas is a small but growing source of income for
native people who collect the fruits and are typically paid by weight. Relative
ease of collection, and abundance of fruits on beaches, makes tamanu harvesting
a desirable income-producing activity. The development of tamanu oil production
in Vanuatu has turned a natural forest product of no prior significant local
use into a commodity of financial value. Revenues from collection contribute
positively to small village economies.
Summary
Tamanu oil is an excellent example of a traditional remedy
that has percolated to broader attention due to a combination of effective use
in traditional settings and scientific research supporting its traditional
uses. Tamanu oil offers relief for common skin problems and has demonstrated
significant benefit in hospital settings as a first aid treatment in cases of
serious burns.
Tamanu oil fulfills three significant ideals: a healing
benefit to users; the collection of the nuts and manufacture of the oil cause
no damage to the environment; and the collection and processing of the nuts
provides income to indigenous people, enhancing the local economies of small
communities.
Chris Kilham is Explorer-in-Residence at the University
Of Massachusetts at Amherst Medicinal Plant Program. He has investigated tamanu
oil in the Pacific islands for the last seven years and works actively with
native people in Vanuatu, South Pacific, in the development of the tamanu oil
trade, in which he has a commercial interest. He has authored several books and
numerous articles.
References:
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2. Petard P. Tahiti-Polynesian medicinal plants and
Tahitian remedies. Noumea, New Caledonia:
South Pacific Commission; 1972.
3. Pillai SN, Desai MV, Shah HM. Antihelminthic properties
of punnakai cake (Calophyllum inophyllum).
Indian Journal of Mycology and Plant Pathology. 1974;4(2):145-50.
4. Whistler WA. Tongan Herbal Medicine. Honolulu: University of Hawaii Press; 1992.
5. Jeanson M. Anti-leprous plants not belonging to the
Flacourtiaceae family [in French]. Bulletin of National Society of
Acclimation on France, 1938.
6. Chevalier J. Study on a new cicatrizing agent for
cutaneous and mucous wounds, oil of Calophyllum inophyllum [doctoral thesis]. Paris, France: Institut de
Biologie Normale Superieure; October 1951.
7. Arora RB, Mathur CN, Seth SDH. Calophylloide, a complex
coumarin anticoagulant from Calophyllum inophyllum Lin. Journal Of Pharmacy and Pharmacology 1962;14:534.
8. Bhalla TN, Saxena RC, Nigam SK, Misra G, Bhargava KP.
Calophyllolide: a new nonsteroidal anti-inflammatory agent. Indian J Med
Res. November 1980;72:762-5.
9. Bhushan B, Rangaswami S, Seshadri TR. Calaustralin, a new
4-phenylcoumarin from the seed oil of Calophyllum inophyllum Linn. Indian Journal of Chemistry. July 1975;13:746-7.
10. Gopalakrishnan C, Shankaranarayanan D, Nazimudeen SK,
Viswanathan S, Kameswaran L. Anti-inflammatory and C.N.S. depressant activities
of xanthones from Calophyllum inophyllum
and Mesua ferrea. Indian
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calophyllolide, a non-steroidal anti-inflammatory agent, on capillary
permeability. Journal of Medicinal Plant Research. 1982;44:246-8.
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VU. Antimicrobial studies on fractions and pure compounds of Calophyllum
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Antibacterial activity of xanthones from Calophyllum inophyllum L. Arogya Journal of Health Science. 1986;XII:48-9.
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Plants. Honolulu: Bishop Museum Press;
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18. Sidi E. Oil of Calophyllum inophyllum in dermatology. La vie medicale. May 1955:82-8.
19. Pocidalo JJ, Chaslot M. Oil of Calophyllum inophyllum on experimental burns [separate report]. Communication
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20. U.S. Department of Agriculture, Agricultural Research Service. Dr. Duke’s
Phytochemical and Ethnobotanical Databases Web site. Available at: <www.ars-grin.gov/cgi-bin/duke/chem-activities.pl>.
Accessed October 3, 2003.
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site. Available at: <www.medinfo.ufl.edu/
year2/mmid/bms5300/bugs/>. Accessed October 3, 2003.
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