Issue:
92
Page: 58-62
Norman R. Farnsworth: Renowned Medicinal Plant Researcher Dies at 81
by Mark Blumenthal
HerbalGram.
2010; American Botanical Council Renowned
pharmacognosist and internationally respected medicinal plant
research expert, Norman R. Farnsworth, PhD, died on September 10 at a
Chicago hospital at the age of 81. He had been in declining health
for months, suffering from long-term congestive heart failure and
Type 2 diabetes.
Prof.
Farnsworth was born on March 23, 1930 in Lynne, Massachusetts. He was
a veteran of the Korean War, drafted into the US Army in 1949 at the
age of 18. PFC Farnsworth served in the Third Infantry Division,
Seventh Regimental Combat Team. After being seriously wounded in the
winter of 1950, he was awarded the Korean Ribbon with Four Battle
Stars, the Combat Medical Badge, and Bronze Star with a “V”
device.
Prof.
Farnsworth received his degree in pharmacy from the Massachusetts
College of Pharmacy in 1953 and his doctorate in pharmacognosy—the
study of drugs from natural origins (including medicinal plants,
microbes, marine organisms, and fungi)—from the University of
Pittsburgh (Pitt) in 1959. At Pitt, he helped institute a
pharmacognosy PhD program and served as its first chairman.
In
1970, Prof. Farnsworth left Pitt for a post in the College of
Pharmacy at the University of Illinois at Chicago (UIC), where he
served as head of the Department of Pharmacognosy and Pharmacology
from 1970-1982. At UIC, he was also Research Professor of
Pharmacognosy, Director of the Pharmacognosy Graduate Program, and
Director of the World Health Organization (WHO) Program for
Collaborative Research in the Pharmaceutical Sciences—a
multidisciplinary program that brought together, for the first time,
scientists in numerous fields of medicinal plant research to
collaborate on drug discovery from medicinal plants. In 1988, he was
named Senior University Scholar at UIC. He held the title of
Distinguished Professor of Pharmacognosy, which he received for his
“scholarship, creativity and leadership,” from 2001 until his
death.
As
head of the pharmacognosy graduate program at UIC, he mentored more
than 100 doctorate and 30 graduate students. Also, he had said he
“personally” mentored about 30 PhD and 5 MS students, as well as
mentored or co-mentored 30 post-doctoral fellows.
Prof.
Farnsworth was an internationally recognized scholar and initiator or
co-initiator of many significant projects in the fields of
pharmacognosy and medicinal plant research. Among numerous other
accomplishments, he was a founding member of both the American
Society of Pharmacognosy (ASP) in 1959 and the Society for Economic
Botany (SEB) in 1959.
In
1975, Prof. Farnsworth created the NAPRALERT (Natural Products Alert)
Database at UIC, the world's first computerized database of
ethnobotany, chemistry, pharmacology, toxicology, and clinical trials
on medicinal plants.
In
1974,
Prof.
Farnsworth was one of 12 members of the first delegation of
scientists from the United States to travel to the People’s
Republic of China to study traditional Chinese herbal medicine. The
American Herbal Pharmacology Delegation’s excursion resulted in the
publication of Herbal
Pharmacology in the People’s Republic of China by
the National Academy of Sciences in 1975.
Prof.
Farnsworth also was Principal Investigator and Director of the
Botanical Dietary Supplements for Women’s Health Center at UIC,
which was funded by the National Center for Complementary and
Alternative Medicine at the National Institutes of Health.
The
author and co-author of hundreds of research papers published in
peer-reviewed journals, Prof. Farnsworth co-founded the peer-reviewed
journal Phytomedicine,
the International
Journal of Phytotherapy and Phytopharmacology,
along with Professor Hildebert Wagner, PhD, at the University of
Munich, who remains the journal’s editor-in-chief. This journal is
now acknowledged as one of the leading scientific journals in the
field.
Among
many other organizations and publications with which he was involved,
Prof. Farnsworth was also a co-founder of the American Botanical
Council (ABC), and the longest-serving member of its Board of
Trustees. In 2005, ABC established its Norman R. Farnsworth
Excellence in Botanical Research Award, given to medicinal plant
researchers who have made significant contributions to the field of
medicinal plants and herbal dietary supplements.
Also
in 2005, the ASP renamed its annual Research Achievement Award in
honor of Prof. Farnsworth, given to outstanding members of the
medicinal plant research community. In 2010, UIC established the
Norman R. Farnsworth Professor in Pharmacognosy Endowed
Professorship, which is currently chaired by Prof. Chuan-Tao Che,
PhD, one of Prof. Farnsworth’s former doctoral students.
Prof.
Farnsworth was the recipient of numerous awards and honorary degrees
from around the world, including the SEB’s Distinguished Economic
Botanist Award in 1983. In the 1990s, he was a member of the
Commission on Dietary Supplement Labels, established by President
Bill Clinton as part of the provisions of the Dietary Supplement
Health and Education Act of 1994 (DSHEA) to develop recommendations
for the review of the quality, safety, benefits, and appropriate
labeling of dietary supplements.
A
larger-than-life figure, Prof. Farnsworth was rarely seen without his
trademark Marsh Wheeling cigars in his mouth, even long after he was
forced to give up smoking. As public venues allowing smoking
diminished over the past 2 decades, Prof. Farnsworth would often be
seen in a restaurant or public area with one of his cigars in his
mouth, even after being admonished by waiters. He would point out the
obvious fact that he was not smoking and that the cigar was not lit,
and would continue to keep the cigar in his mouth, seeming to relish
the opportunity to keep walking up to the line, but not exceeding it.
He
was highly respected and admired in life, and is now remembered
fondly by his former students, mentees, and friends. Often seen as
brash and outspoken, frequently critical of other scientists and
institutions that to him were guilty of producing
less-than-acceptable work or policies, Prof. Farnsworth pushed his
students and all those around him to strive to the highest degree of
academic and professional excellence. And underneath the brash
veneer, was a man who was seen by his colleagues and students as
extraordinarily generous with his time and personal funds.
His
long-time friend and colleague of 56 years, UIC Professor (ret.)
Harry H.S. Fong, PhD, once said, “Everyone who has come into
contact with Norman Farnsworth has a ‘Farnsworth story’ or 2 to
tell.” Dr. Fong recalled that Farnsworth—who continued working up
until shortly before his illness—recently noted that Dr. Fong,
his former graduate student, had retired, as an example of how long
Prof. Farnsworth had hoped to be able to continue his never-ending
work in medicinal plant research.
Another
phrase used to describe Prof. Farnsworth is the “quintessential
renaissance man,” as he was called in an editorial in the ASP’s
Journal
of Natural Products
by his colleagues Dr. Fong, Geoffrey A. Cordell, PhD, and A. Douglas
Kinghorn, PhD, the journal’s editor-in-chief: “To fully depict
Farnsworth, one needs to write a book,” said Dr. Fong.
In
addition to being an ASP founder and its second president (the late
Prof. Varro E. Tyler, also an early ABC Trustee, was the first),
Prof. Farnsworth relished the role of being the official “roaster”
of subsequent ASP presidents. Every year at its annual meeting and
scientific conference, one of the true highlights was Farnsworth’s
humorous satire, or “roast,” of the ASP’s out-going president—a
tradition continued for almost 50 years. In the days and weeks since
his passing, numerous colleagues have expressed their laments that
Prof. Farnsworth—with his unlit, well-chewed cigar in mouth—would
no longer be conducting this light-hearted tradition. It will now be
ably carried on by Prof. Farnsworth’s former student graduate Barry
O’Keefe, PhD, of the National Cancer Institute.
Dr.
Fong shared several anecdotes about Prof. Farnsworth. One story
involved his propensity for cigars. “On every lab bench and in
every office that Norm has spent any length of time at the University
of Pittsburgh and at University of Illinois at Chicago, one will find
a littering of chewed remains of Marsh Wheeling cigar butts,” said
Dr. Fong. “In fact, such mementos can even be found in Munich,
Germany. When he was a visiting professor in Prof. H. Wagner’s lab
in 1966, I had the ‘pleasure’ of regularly mailing boxes of Marsh
Wheeling cigars labeled as ‘Investigational Material: Of no
commercial interest’ to the Institute in Munich.”
However,
when it comes to picking out Prof. Farnsworth’s most important
accomplishment, Dr. Fong could not choose: “It is not possible to
pinpoint any one piece of Norm’s work as being most influential and
important,” said Dr. Fong. “Rather, it is his body of work that
will constitute his legacy.”
ABC
Founder and Executive Director Mark Blumenthal first met Farnsworth
in 1977 at the Herb Trade Association’s Herb Symposium in Santa
Cruz, California. After a decade of a growing mentorship and
friendship with Blumenthal, Prof. Farnsworth—along with economic
botanist and ethnobotanist James A. Duke, PhD—were the first to
agree to help found ABC and serve on its Board of Trustees.
“Norm
was a force of nature—a man with incredible energy and profound and
endless commitment to the world of medicinal plant research. There is
no one like him in the profession of pharmacognosy and other fields
of medicinal plant research,” said Blumenthal.
“He
was like a father or uncle figure to many of his 130-plus graduate
students and post-docs, creating a ‘family’ of medicinal plant
researchers who are now working in many institutions internationally.
No matter how busy he was—and he carried an incredible workload not
matched by many in any field of medicinal plant science—Norm would
always take time to talk to students and fellow colleagues,”
Blumenthal noted.
“As
he neared the last few years of his life and he began to disengage
from many of his former associations and responsibilities, Norm still
remained active on the Board of ABC, attending all on-site and
teleconference meetings, asking questions about budget issues,
organization, administration, policy decisions, etc. All of us on the
ABC Board were—and still are—grateful for his continued
association with ABC. We were amazed with his interest in and
knowledge of details of the organization, and his profound
commitment to the success of ABC’s unique nonprofit educational
mission to spread the scientific basis supporting the responsible use
of herbs, medicinal plants, and phytomedicines,” said Blumenthal.
One
of Prof. Farnsworth and Dr. Fong’s former students Daniel
Fabricant, PhD, is now director of the Division of Dietary Supplement
Programs at the US Food and Drug Administration, and formerly served
as Vice President of Science and Regulatory Affairs at the Natural
Products Association, an industry trade group. Dr. Fabricant said
that he chose UIC because of Dr. Farnsworth and his legacy there.
“He’s a straight shooter, he doesn’t put on airs, and he’s
very disarming. He’s easy to gravitate to because of these unique
qualities,” said Dr. Fabricant. “He’s been my mentor, a hero,
and a friend.”
“He
has launched a thousand careers, including my own,” said Gail
Mahady, PhD, a clinical pharmacognosist who also met Prof. Farnsworth
during graduate school, and who headed the project at UIC to produce
monographs on herbal medicines for WHO. “For that I will be
eternally grateful.”
Prof.
Farnsworth is survived by his devoted wife Priscilla Marston
Farnsworth, his brother, Bruce, and sister-in-law, Donna, of
Massachusetts, a niece and nephew, and hundreds of graduate students,
PhDs, post-doctoral fellows, and close colleagues who will always
cherish his beloved memory.
A
wake and viewing were held in Downers Grove, Illinois, on September
13. A memorial service for Prof. Farnsworth was held September 14 at
the North Shore Baptist Church in Chicago with funeral and
burial with military honors in Lynn, Massachusetts, on September 16
at Pine Grove Cemetery.
Quotes
I
am heartbroken, and the loss is felt out here in [the South Pacific
island of] Pohnpei. He was, and is, a giant among giants, and the
last of the close collaborators of Richard Evans Schultes. He was one
of those heroes to us graduate students in the ‘70s, a wonderful
travel companion and extraordinary mentor.
Michael
J. Balick, PhD
Vice
President for Botanical Science, Director and Philecology Curator
Institute
of Economic Botany
New
York Botanical Garden
Norm
was a personal friend and mentor to me and many others in the
botanical and pharmacognosy communities. He was an exceptional
person on many levels. Norm had been ill for quite some time,
and so I am relieved that his suffering is over but saddened that we
no longer have his unique wisdom, humor, and generosity with us. We
must now do our best to carry forward and carry on his tradition and
legacy of respect of and interest in medicinal plants and the native
populations who have used these plants to our collective benefit.
Loren
Israelsen
Executive
Director
United
Natural Products Alliance
The
world is a much quieter and less interesting place now that Norm is
gone.
Michael
Tempesta, PhD
Managing
Partner
Phenolics,
LLC
What
a wonderful feisty irreplaceable guy! He held a torch for many
years and we just would not be where we are without him. Our thoughts
are with the many, many people whose lives he touched.
Peggy
Brevoort
President
Brevoort,
LLC, Kapa’au, HI
As
a former postdoc at UIC (actually working directly with Geoff Cordell
at the time), I felt very saddened by this loss. On the one hand, he
was one of these characters larger than life; on the other hand, a
scientist who had this vision of multidisciplinary research that
enabled him to attract an extraordinary bunch of talented scientists.
Matthias
Hamburger, PhD
Professor
of Pharmaceutical Biology and Head of Department of Pharmaceutical
Sciences
University
of Basel (Switzerland)
As
I think back, I recall the last ride we took together in a cab
to the airport. I can almost smell his unlit cigar as it hung from
his lips while we talked. When I offered to split the cab fare,
he almost chastised me and forced the driver to only take his
money—my North Carolina money was not good up there! He truly
leaves us a legacy with many, many extensions just like the
roots of the medicinal plants he researched so passionately!
Edward
Fletcher, PhD
COO,
Botanical Division
Strategic
Sourcing, Inc.
My
fondest memory of Norm was when he went to Ghana with Dan and me in
the mid-90s to visit Dr. Oku Ampofo. Norm had an absolutely wonderful
time, both visiting with Dr. Ampofo (who was then restricted to bed)
and with the Centre for Scientific Research into Plant Medicine. He
had everyone laughing all the time, and he gave a major public
lecture at the British Consulate. He found that people had been
naming children after him and said we, as newlyweds, should name our
first child after him. We said that we weren't planning to have any
more children, but Dan mentioned that we were going to get a dog, and
he said that we should name our dog after him. We got a gorgeous
Viszula whom we named Farnsworth, and he kept us laughing almost as
much as his namesake had. I know that everyone has a Farnsworth
story, and I cherish all of mine from that trip! The world has lost a
real treasure.
Diane
Winn
Owner,
Founder, and Chair
Phytica
Inc.
I
am indeed saddened by the news of Prof. Norman Farnsworth, a
dedicated pharmacognosist and botanist. I have not met the "man,”
but his works stimulated me to continue on my passion over 30
years. He will be greatly missed.
Diane
Robertson
Kingston,
Jamaica
The
news of sad demise of Professor Norman R. Farnsworth came as a
dampener of the spirits to the members of the Society for New Age
Herbals in India. Being personally involved in the efforts of
new drug development from plant sources, it was virtually impossible
not to come across the contributions of Prof. Norman R. Farnsworth.
The kind of reviews and approaches he has published on the subject
are monumental and unparalleled.
C.P.
Khare
Founder
and President
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