Re: Supplementation with Coffee Berry Increases Antioxidant Capacity in Athletes
Ostojic SM, Stojanovic, MD, Djordjevic B, Jourkesh M, Vasiljevic N. The effects of a 4-week coffee berry supplementation on antioxidant status, endurance, and anaerobic performance in college athletes. Res Sports Med. 2008;16: 1-14.
Physical exercise increases oxygen consumption, which, in
turn, increases the production of reactive oxygen species and free radicals.
The increase in antioxidant capacity known to occur with endurance training may
not be sufficient to neutralize this increase in free radical production. Thus,
nutritional supplements rich in bioavailable antioxidants have become
particularly popular in physically active persons over the past decade.
However, the effects of antioxidant supplements on antioxidant status, cellular
structure, and performance are not clearly understood. In physically active
persons, antioxidant supplementation has been shown to have beneficial effects
on performance and recovery (e.g., increased energy levels and a decreased risk
of muscle injury) in some studies but to cause decreases in training efficiency
and in cellular antioxidant adaptation in other studies. Therefore, the benefit
of antioxidant supplementation in athletes is controversial. The objective of
this study was to evaluate changes in total antioxidant capacity (TAC) and in
aerobic and anaerobic performance in college athletes after supplementation
with coffee (Coffea spp.) berry (CB).
Twenty healthy college athletes (14 men and 6 women) were
recruited for this study, which was conducted at the University of Belgrade,
Serbia. The subjects were randomly assigned to receive CB capsules (400 mg each
twice daily) or placebo capsules (cellulose) for 28 days. Both the CB and
placebo capsules were manufactured by Futureceuticals (Momence, Illinois).
The subjects maintained their habitual "consumption habits"
throughout the study period, but a week before baseline testing and for 4 weeks
prior to experimental testing a standardized diet was employed. Between tests,
similar resistance-training programs were monitored by a strength and
conditioning coach. No prolonged exercise occurred for 48 hours before the
experiments, performed by all on the same day and in the same order. After
completing a 15-minute warm-up consisting of sprints, the subjects completed a
60-second vertical jump test. Heart rate was measured before (baseline),
during, and after the test. The highest heart rate was recorded as HRmax,
and the decrease in heart rate in the first minute after the test was recorded
as the heart rate recovery (HRR) index. Blood samples were collected at baseline
and after the test for the measurement of glucose, total cholesterol,
high-density and low-density lipoproteins, triglycerides, and TAC. Blood
lactate concentrations were measured 5 minutes (Lactmax) and 10
minutes (Lactrec) after the test. Maximal oxygen uptake was also
measured during exercise. The subjects were instructed to report any adverse
side effects experienced. P values >0.05 indicated significant differences.
No significant differences in baseline measures were
observed between the CB and placebo groups. The mean (± SD) TAC was significantly
greater in the CB group than in the placebo group after supplementation and was
significantly greater after supplementation (1.66 ± 0.16 mmol/L) than at
baseline (1.54 ±
0.13 mmol/L) in the CB group. The mean (± SD) HRR index was also
significantly greater in the CB group than in the placebo group after
supplementation and was significantly greater after supplementation (38 ± 4
beats/min) than at baseline (32 ± 9 beats/min) in the CB group. Lactrec
decreased significantly in the CB group after supplementation (from 7.6 ± 4.2
to 5.5 ±
2.6 mmol/L) and was significantly lower in the CB group than in the placebo
group after supplementation. Glucose, total cholesterol, high-density and
low-density lipoproteins, triglycerides, HRmax, Lactmax,
average anaerobic power, maximal oxygen uptake, and the index of anaerobic
fatigue did not change significantly from baseline and were not significantly
different between the CB and placebo groups after supplementation. None of the
subjects reported any adverse side effects.
The results indicate that CB supplementation slightly but
significantly increased TAC but had only "minimal effects" on the
recovery parameters measured after exercise in college athletes. To the
authors' knowledge, this study was the first to directly analyze the effects of
CB supplementation on antioxidant status and exercise performance in athletes.
Because no data are available in peer-reviewed journals to corroborate these
data, the authors recommend that additional research be conducted to determine
the possible underlying mechanisms for the observed effects. Possible variables
to be studied include the changes in dosage and duration and the nature and
intensity of training on anaerobic performance and endurance.