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- Green Tea (Camellia sinensis)
- Hibiscus (Sour Tea; Hibiscus sabdariffa)
- Type 2 Diabetes
- Blood Pressure
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Date:
08-15-2013 | HC# 071331-478
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Re: Clinical Trial Demonstrates that Drinking Green Tea or Hibiscus Tea May Lower Blood Pressure in Patients with Diabetes
Mozaffari-Khosravi
H, Ahadi Z, Barzegar K. The effect of green tea and sour tea on blood pressure
of patients with type 2 diabetes: a randomized clinical trial. J Diet Suppl. 2013;10(2):105-115.
Diabetes mellitus, a common chronic metabolic disorder, is increasing in prevalence
worldwide, with about 6.4% of adults aged 20 to 79 years reported in 2010 to
have the disease.1 Herbal therapies are often used to prevent and
control the complications of diabetes. Specifically, the chemical constituents
of tea, including flavonoids, are thought to help control the metabolic and
vascular complications of the disease. Green tea (GT; Camellia sinensis) and hibiscus (sour tea; Hibiscus sabdariffa) are reported to have beneficial health
effects. These authors conducted a randomized, clinical trial to compare the effects
of drinking these 2 teas in patients with mild hypertension and type 2 diabetes
mellitus.
Supported
by the Yazd Diabetes Research Center in Yazd, Iran, the authors recruited 100
patients who fit the following criteria: aged between 30 and 60 years with a
5-year history of diabetes; blood pressure of 120-139/80-89 mmHg; no
nephropathic or other expressive symptoms; no insulin use; no consumption of
antioxidant complements, vitamins, minerals, or fish oil for the previous 6
months; and no history of renal, thyroid, hepatic, or cardiovascular disorders.
Patients
were randomly assigned to either the hibiscus tea (HT) group (n=46) or the GT group
(n=48); there were 6 patient dropouts, leaving a total of 94 patients who
completed the study. Patients were given similar GT and HT bags and instructed
to drink the tea 3 times daily (2 hours after each meal) for 4 weeks. Both
types of tea were purchased from "reliable herbal shops and approved by
the naturist practitioners." Those in the GT group were instructed to boil
the 3 g GT bags in 150 mL of water and wait 5 minutes before drinking the tea.
In the HT group, the patients boiled the 3 g HT bags in 150 mL of water, waited
10 to 15 minutes, and then drank the tea in one sitting.
Overnight
fasting blood samples were drawn before and after the intervention to measure
fasting blood sugar (FBS) levels. Body measurement parameters, including body
weight, height, and body mass index (BMI), were recorded at baseline and at the
end of 4 weeks. The patients' systolic blood pressure (SBP) and diastolic blood
pressure (DBP) were measured on day 1, day 15, and at the end of the study. A
24-hour dietary recall questionnaire was used to determine the patients' daily
dietary intake. The authors report an 89% compliance rate in the HT group and
91% in the GT group. No adverse effects were reported. No within- or between-group
changes were seen in mean FBS concentration, weight, or BMI during the 4-week study.
The
SBP and DBP of both groups decreased significantly at the end of the study
compared with baseline (P<0.001); however, the mean differences were not
statistically significant between the 2 groups at the study's end. Compared
with baseline values, blood pressure decreased by 39.6% in the GT group and by
43.5% in the HT group. Pulse pressures, body weight, and BMI decreased in both
groups, though not significantly, and the mean changes were also not
statistically different between the 2 groups at the study's end.
According
to the authors, GT is thought to affect blood pressure through its polyphenol epigallocatechin-3-gallate
(EGCG), which increases nitric oxide (NO) production.2 The mechanism
accounting for the decreased blood pressure associated with HT may be the
release of NO from the endothelium of vessels and the prevention of calcium
penetration to vascular smooth muscle cells.3
This
study is limited by the lack of a control group, no double-blinding, and no
measurement of sodium, potassium, or calcium concentrations or specific amounts
of the various active constituents of tea, such as caffeine.
Acknowledging
those limitations, the authors conclude that their study "revealed that
mildly hypertensive type 2 diabetic individuals who drink three glasses of
green or sour [hibiscus] tea daily for 4 weeks show significant decreased
systolic and diastolic blood pressures," and they suggest that patients
with diabetes who are hypertensive drink those teas daily.
―Shari Henson
References
1Azimi-Nezhad M,
Ghayour-Mobarhan M, Parizadeh MR, et al. Prevalence of type 2 diabetes mellitus
in Iran and its relationship with gender, urbanisation, education, marital status and occupation. Singapore Med J.
2008;49(7):571-576.
2Wolfram S. Effects of
green tea and EGCG on cardiovascular and metabolic health. J Am Coll Nutr. 2007;26(4):373S-388S.
3Mahadevan N, Shivali, Kamboj P. Hibiscus sabdariffa Linn.–An
overview. Natural Product Radiance. 2009;8(1):77-83.
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