FWD 2 Botanical Adulterants Monitor - American Botanical Council


Dear Reader

For the second time since its inception, BAPP has been recognized by a media organization for its work. After Nutritional Outlook magazine’s “Best of the Industry 2016” award in December 2016, BAPP received the Editor’s award for “Industry Initiative of the Year” by NutraIngredients-USA, another of the leading industry trade publications in the United States. BAPP was chosen for the award as “an exemplary educational resource about adulteration in the botanical supply chain.”

The release of the Grape Seed Extract Laboratory Guidance Document (LGD) in February marked the 50th peer-reviewed publication of the ABC-AHP-NCNPR Botanical Adulterants Prevention Program (BAPP). Reaching the 50-publications milestone would not have been possible without all those who have given their time to help write, review, and publish these papers, and all the companies, institutions, associations, and organizations which have supported BAPP financially or by writing a letter of endorsement and support. While getting to “50” papers may be a nice achievement, our ultimate goal is not to create as many publications as possible, but to improve the quality and integrity of herbal dietary supplements and other botanically-based products for the benefit of the consumer. As such, we hope that these publications have made a positive impact on the authenticity of botanical ingredients throughout the industry supply network.


  Stefan Gafner, PhD
Chief Science Officer, ABC
Technical Director, ABC-AHP-NCNPR Botanical Adulterants Program

ABC-AHP-NCNPR Botanical Adulterants Program


Recent News 

Botanical Adulterants Prevention Program Publishes Grape Seed Extract Laboratory Guidance Document 

BAPP LGD Grapefruit Seed Extract

The Grape Seed Extract Laboratory Guidance Document, published in February, 2019, is the result of a collaboration between Steve A. Kupina and Mark A. Kelm, PhD, from botanical ingredient manufacturer Polyphenolics, Maria J. Monagas, PhD, from the United States Pharmacopeial (USP) Convention, and Stefan Gafner, PhD from the American Botanical Council (ABC). Grape seed-derived dietary supplements have been shown to improve parameters related to cardiovascular health in clinical trials.

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Aloe Vera Bulletin Published by Botanical Adulterants Prevention Program

BAPP BAB Aloe Vera

Liquids and powders obtained from the leaf of aloe vera are widely used as ingredients in dietary supplement, personal care, and cosmetic products. In addition, aloe vera leaf juice ingredients for internal consumption are popular in the food and beverage industry. The total global market value of aloe vera leaf gel (as an ingredient for all types of products) was estimated at US $507 million in 2017.

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NutraIngredients-USA Recognizes Botanical Adulterants Prevention Program with Editors Award for Industry Initiative of the Year 

The ABC-AHP-NCNPR Botanical Adulterants Prevention Program (BAPP) received the Editor’s Award for “Industry Initiative of the Year” by NutraIngredients-USA, one of the leading natural products and dietary supplement industry trade publications in the United States.

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ABC-AHP-NCNPR Botanical Adulterants Prevention Program Welcomes New Supporters and Underwriters 

The ABC-AHP-NCNPR Botanical Adulterants Prevention Program is grateful to the following companies that have recently committed to financially underwriting the Program:
  • College of Practitioners of Phytotherapy
  • Informa
  • LifeSeasons, Inc.
  • Nutrasource Diagnostics, Inc.
BAPP also gratefully acknowledges the endorsement of the World Naturopathic Federation.

Upcoming Events

Below are descriptions and links to some of the upcoming conferences, seminars, and workshops that may be of interest to learn more on adulteration.

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Previous Issues of “Botanical Adulterants Monitor”

Available here.

Regulatory Alerts

Recalls of Pyrrolizidine Alkaloid-Containing Spices and Food Supplements in Europe

In the time period between March and June 2019, alerts for 19 products containing botanical ingredients contaminated with potentially toxic pyrrolizidine alkaloids (PAs) have been issued by the European Commission on its Rapid Alert System for Food and Feed (RASFF) portal.

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Science Update

Two-Step Screening Using Mid-Infrared and HPLC-UV Fingerprints to Detect Undeclared Herbal Ingredients in Weight-Loss and Erectile Dysfunction Food Supplements

Deconinck E, Vanhamme M, Bothy JL, Courselle P. A strategy based on fingerprinting and chemometrics for the detection of regulated plant food supplements from the Belgian market. J Pharm Biomed Anal. 2019;166:189-196.

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St. John's Wort

NMR versus HPTLC to Assess the Variability in Crude St. John’s Wort Raw Material

Reviewed: Scotti F, Löbel K, Booker A, Heinrich M. St. John’s wort products – how variable is the primary material? Front Plant Sci. 2019;9:1973.

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Anthocyanin Composition of Açaí Dietary Supplement and Conventional Food Products

Reviewed: Lee J. Anthocyanins of açaí products in the United States. NSF Journal. 2019;14-15:14-21.

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Composition in Phenolic Compounds of Black Chokeberry Fruit, Pomace, Juice, and Powdered Commercial Samples

Reviewed: Rodríguez-Werner M, Winterhalter P, Esatbeyoglu E. Phenolic composition, radical scavenging activity and an approach for authentication of Aronia melanocarpa berries, juice, and pomace. J Food Sci. 2019; doi: 10.1111/1750-3841.14660. [Epub ahead of print].

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Over Half of the Dietary Supplement Products Linked to Liver Injury May be Mislabeled

Reviewed: Navarro V, Avula B, Khan IA, Verma M, Seeff L, Serrano J, Stolz A, Fontana R, Ahmad J. The contents of herbal and dietary supplement implicated in liver injury in the United States are frequently mislabeled. Hepatol Commun. 2019;3(6):792-794.



Useful Links and Resources

For more information and updates on the work of the three partner organizations of the ABC-AHP-NCNPR Botanical Adulterants Program, please visit ABC at www.herbalgram.org, AHP at www.herbal-ahp.org, and NCNPR at www.pharmacy.olemiss.edu/ncnpr.

Other Helpful Resources and Links

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About the

The ABC-AHP-NCNPR Botanical Adulterants Program is a consortium of independent nonprofit organizations whose mission relates to education, scientific research, and quality of botanical dietary ingredients and related plant-derived materials. The consortium is headed by three nonprofit groups dealing with education and research on medicinal herbs and other beneficial plants: the American Botanical Council, the American Herbal Pharmacopoeia, and the National Center for Natural Products Research at the University of Mississippi. The program is underwritten or endorsed by more than 130 natural products industry companies, independent analytical laboratories, contract research organizations, nonprofit and professional organizations, trade associations, accredited institutions of education in natural medicine, law firms, and media companies that are involved in the production, supply, manufacture, distribution, marketing, analysis, research, and/or education of herbal dietary ingredients and supplements, in the United States and internationally. All publications of the Program are available free-access on its homepage including the “Botanical Adulterants Monitor,” an e-newsletter that conveys Program news, regulatory updates, and recent scientific publications related to adulteration, contamination, identity, and authenticity of botanical raw materials, extracts, and essential oils. Companies, organizations, foundations, and/or individuals interested in supporting this program are invited to contact Ms. Denise Meikel, ABC Development Director, at (512) 926-4900, ext. 120, or by email.


Thank You to Our Supporters

Underwriters and Supporters of the ABC-AHP-NCNPR Botanical Adulterants Program (as of August 9, 2019)*

*By acknowledging the generous support of these companies and organizations, ABC, AHP, and NCNPR are not endorsing any ingredients or products that may be produced or marketed by them.

Financial Underwriters

21st Century Healthcare

AdvoCare International L.P.

Agilent Technologies, Inc.

Aloecorp, Inc.

Amen Clinics

Amway/Nutrilite Health Institute

Arbonne International

Arizona Nutritional Supplements

Artemis International, Inc.

Atrium Innovations

Aveda Corporation

Beachbody, LLC

BI Nutraceuticals


Bionorica SE



Botanical Liaisons

Bruker BioSpin


Cepham, Inc.

Chemi Nutra

CNCA Health

Complete Phytochemical Solutions

Crila Health

dicentra, Inc.

Doctor’s Best

Dr. Bronner's Magic Soaps

DolCas Biotech, LLC

Douglas Laboratories

Draco Natural Products

Emerson Ecologics

Enzymatic Therapy, Inc.

Ethical Naturals, Inc.

Eu Yan Sang International




Flavex Naturextrakte GmbH


Fruit d'Or

Gaia Herbs

GE Nutrients, Inc.

Global Health Industries

GNC, Inc.

Healthy Lifestyle Brands, LLC

Helios Corp.

Herb Pharm

Herbalife International, Inc.

Horphag Research


Indena USA, Inc.

Indfrag Limited


Ingredient Identity

Ixoreal Biomed, Inc.

Jarrow Formulas

K. Patel Phyto Extractions Pvt. Ltd

Layn USA, Inc.

LifeSeasons, Inc.


Markan Global Enterprises, Inc.

Financial Underwriters

Martin Bauer, Inc.

MediHerb / Integria Healthcare

Metagenics, Inc.

MIDI, Inc.

Natreon, Inc.


Natural Alternatives International, Inc.

Natural Factors Nutritional Products, Inc.
   /Bioclinic Naturals

Natural Grocers by Vitamin Cottage

Natural Remedies Pvt. Ltd.

Nature's Answer

Nature's Sunshine Products

Nature's Way


Naturex, Inc.

NBTY, Inc.

New Chapter, Inc.

The New Frontier Foundation Fund of the Greater Cedar Rapids Community Foundation

Ningbo Greenhealth Pharmaceutical Co., Ltd.

Novel Ingredients

NOW Foods

Nu Skin Enterprises/Pharmanex

Nutraceuticals Corp.

NutraSource Diagnostics, Inc.

Organic India

Ortho Molecular Products

Pacific Nutritional Inc.

Paragon Laboratories

Pathway International Pty Limited

Perrigo Company

Pharmatoka SAS

Pharmavite, LLC

Phoenix Formulations

PLT Health Solutions, Inc.

Polyphenolics, Division of Constellation Brands, Inc.

Pure Encapsulations

Rainbow Light Nutritional Systems

Regular Girl

RFI Ingredients, LLC

Rosenbush and Zimmerman Family Fund

Sabinsa Corporation

Schwabe North America


SFI Flordis

Shaklee Corp.

Standard Process, Inc.

Strategic Sourcing, Inc.

Taiyo International, Inc.

Thorne Research, Inc.

Tishcon Corp.

Tomorrow's Nutrition

Traditional Medicinals, Inc.

TSI Group


Univera, Inc.

Valensa International

V.D.F. FutureCeuticals

Verdure Sciences

Vitamin Shoppe

VitaQuest International

Whole Foods Market

Trade Associations

American Herbal Products Association (US)

Australian Self Medication Industry (Australia)

Australian Tea Tree Industry Association (Australia)

British Herbal Medicine Association (UK)

Canadian Health Food Association (Canada)

Complementary Medicines Australia (Australia)

Consumer Healthcare Products Association (US)

Council for Responsible Nutrition (US)

International Alliance of Dietary/Food Supplement Associations (IADSA)

National Animal Supplement Council (US)

Natural Products Association (US)

Natural Products New Zealand (NZ)

United Natural Products Alliance (US)

Nonprofit/Professional Associations

Academy of Integrative Health & Medicine

American Association of Naturopathic Physicians

American Herbalists Guild

American Society of Pharmacognosy

AOAC International

Council of Colleges of Acupuncture and Oriental Medicine

Homeopathic Pharmacopoeia Convention of the United States
Integrative Healthcare Policy Consortium

Irish Register of Herbalists (IRE)

National Institute of Medical Herbalists (UK)

Natural Health Products Research Society of Canada (NHPRS Canada)

Personalized Lifestyle Medicine Institute

Society for Medicinal Plant and Natural Product Research (GA)

World Naturopathic Federation 


Bastyr University

Boucher Institute for Naturopathic Medicine

Center for Natural Products Technologies, College of Pharmacy, University of Illinois-Chicago

College of Practitioners of Phytotherapy

Hong Kong Baptist University’s School of Chinese Medicine

National College of Natural Medicine

Southwest College of Naturopathic Medicine

University of Bridgeport College of Naturopathic Medicine
Third-Party Analytical Laboratories

Alkemist Labs

AuthenTechnologies LLC

Bent Creek Institute

BotaniCert (France)

British Columbia Institute of Technology


Covance Laboratories

Creative Accord, LLC

Eurofins Scientific Inc.

Flora Research Labs

NSF International

PhytoLab (Germany)

Spectrix Labs

Tampa Bay Analytical


Alive Publishing Group

Delicious Living


Holistic Primary Care

Informa Exhibitions US

Integrator Blog

Media Relations, Inc.

Modern Healthcare Practitioner

Natural Foods Merchandiser

Natural Medicine Journal

Natural Products INSIDER


Nutraceuticals World


Nutrition Business Journal

Nutrition Industry Executive

Nutritional Outlook

Vitamin Retailer

WholeFoods Magazine


Law Firms & Regulatory Consultants

Amin Talati & Upadhye, LLC

Greenberg Traurig, LLP (James Prochnow)

Law Office of Holly Bayne, P.C.

Robert Forbes & Associates

Susan Brienza, LLC

Ullman, Shapiro & Ullman, LLP

Contract Research Organizations

KGK Synergize


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