Cinchona bark Cinchonae cortex
Chinarinde
Published February 1, 1990
Name of Drug
Cinchonae cortex, cinchona bark.
Composition of Drug
Cinchona bark consists of the dried bark of Cinchona pubescens Vahl (syn. Cinchona succirubra Pavon ex Klotzsch) [Fam. Rubiaceae], or of their variations and hybrids, as well as preparations of cinchona bark in effective dosage.
Uses
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Loss of appetite, peptic discomforts such as bloating and fullness.
Contraindications
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Pregnancy, allergy to cinchona alkaloids, such as quinine and quinidine.
Side Effects
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Occasionally, after taking medicines containing quinine, allergic reactions such as skin allergy or fever may occur. In rare cases, there is an increased tendency to bleeding because of a reduction in the blood platelets (thrombocytopenia). If this happens, a doctor must be consulted immediately.
Warning:A sensitization for quinine or quinidine is possible.
Interactions with Other Drugs
If given simultaneously, increases the effect of anticoagulants.
Dosage
Unless otherwise prescribed:
Daily dosage:
- 1 - 3 g of drug;
- 0.6 - 3 g of cinchona liquid extract with 4 - 5 percent total alkaloids;
- 0.15 - 0.6 g cinchona extract with 15 - 20 percent total alkaloids;
- Preparations with equivalent bitterness value.
Mode of Administration
Comminuted drug and other bitter-tasting galenical preparations to be taken orally.
Action
Stimulation of the secretion of saliva and gastric juice.
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