Cola nut

Colae semen, cola nut.  

Cola nut consists of the endosperm freed from the testa of various Cola species Schott et Endlicher, particularly C.  nitida (Ventenat) Schott et Endlicher [Fam.  Sterculiaceae], as well as its preparations in effective dosage.  

The drug contains at least 1.5 percent methylxanthine (caffeine, theobromine).  

Uses

Mental and physical fatigue.  

Contraindications

Gastric and duodenal ulcers.  

Side Effects

Sleep disorders, over-excitability, nervous restlessness, and gastric irritations may occur.  

Strengthening of the action of psychoanaleptic drugs and caffeine-containing beverages.  

Unless otherwise prescribed:

Daily dosage:

• 2 - 6 g cola nut ( Erg.  B.  6 );
• 0.25 - 0.75 g cola extract ( Erg.  B.  6 );
• 2.5 - 7.5 g cola liquid extract ( Erg.  B.  6 );
• 10 - 30 g cola tincture ( Erg.  B.  6 );
• 60 - 180 g cola wine ( Erg.  B.  6 ).  

Powdered drug and other galenical preparations for internal use.  

From animal experiments:

• Analeptic
• Stimulates production of gastric acid
• Lipolytic
• Increases motility

In humans:

• Compared to methylxanthine, caffeine is a weaker diuretic and positively chronotropic.