FWD 2 Commission E: Echinacea Pallida root

  The Commission E Monographs

Echinacea Pallida root


Echinaceae pallidae radix
Echinacea-pallida-Wurzel
Published August 29, 1992

Name of Drug

Echinaceae pallidae radix, echinacea pallida root.  

Composition of Drug

Echinacea pallida root, consisting of fresh or dried root of Echinacea pallida (Nutt.) Nutt.  [Fam.  Asteraceae], as well as its preparations in effective dosage.  

Pharmacological Properties, Pharmacokinetics, Toxicology

Animal experiment:

  • In a carbon clearance test, alcohol root extracts show an increase in the elimination of carbon particles by a factor of 2.2.  

In vitro:

  • Alcohol root extracts show an increase in phagocytic elements by 23 percent when tested in granulocyte smears at a concentration of 10-4- 10-2mg/ml.  

Clinical Data

Uses

Supportive therapy for influenza-like infections.  

Contraindications

Not to be used when progressive systemic diseases such as the following exist:

Tuberculosis, leukosis, collagenosis, multiple sclerosis, AIDS, HIV infection, and other autoimmune diseases.  

Side Effects

None known.  

Precautions

None.  

Effects on Pregnancy and Lactation

None.  

Interactions with Other Drugs

None known.  

Dosage

Unless otherwise indicated:

Daily dosage:

  • Tincture (1:5) with 50 percent (v/v) ethanol from native dry extract (50 percent ethanol, 7 - 11:1), corresponding to 900 mg herb.  

Information for children's dosage is not available.  

Mode of Administration

Liquid forms for oral administration.  

Duration of Administration

Not longer than 8 weeks.  

Overdosage

None known.  

Special Precautions

None known.  

Effects on Operators of Vehicles and Machinery

None known.