Fixed Combinations of Javanese Turmeric root, Celandine herb, and Wormwood Published December 18, 1991; Revised September 3,1992
Name of Drug
Fixed combinations of Javanese turmeric root, celandine herb, and wormwood.
Composition of Drug
Fixed combinations consisting of:
Javanese turmeric root corresponding to B. Anz. 122, July 6, 1988; Celandine herb corresponding to B. Anz. 90, May 15, 1985; Wormwood corresponding to B. Anz. 228, December 5, 1984;
and their preparations in effective dosage.
Uses
Spastic epigastric discomfort due to functional disorders of the biliary tract.
Contraindications
Obstruction of the biliary tract. If suffering from gallstones, to be used only after consultation with a physician or pharmacist.
Side Effects
Gastric discomfort may occur with extended use.
Interactions with Other Drugs
None known.
Dosage
Unless otherwise prescribed:
Celandine herb must be present at the dosage given in the monograph. The other components of the combination must each be present at 30 - 50 percent of the daily dosage given in the monographs for the individual herbs.
Deviating dosages must be justified for the specific preparations (e.g., comparative bitter values).
Mode of Administration
Comminuted drug and galenical preparations thereof for oral intake.
Actions
For preparations of wormwood and Javanese turmeric root, a choleretic effect is documented; for celandine herb a papaverine-like, mildly spasmolytic effect on the gastrointestinal tract is known. Pharmacological tests for the effectiveness of fixed combinations are not available.
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