Fixed Combinations of Uva Ursi leaf, Goldenrod, and Java tea

Fixed combinations of uva ursi leaf, goldenrod herb, and java tea.  

Fixed combinations consisting of:

Uva ursi leaf corresponding to the monograph published December 5, 1984;
Goldenrod herb corresponding to the monograph published October 15, 1987;
Java tea corresponding to the monograph published March 13, 1986;

as well as their preparations in effective dosage.  

Supportive therapy of inflammatory diseases of the lower urinary tract.  

None known.  

Note:No irrigation therapy in case of edema due to insufficient heart and kidney function.  

Children and patients with a sensitive stomach may experience nausea and vomiting.  

Uva ursi preparations should not be given simultaneously with medications designed to acidify the urine.  

Unless otherwise prescribed:

Uva ursi leaf must be present at a concentration given in the monograph for the single herb.  The other combination components must each correspond to a concentration of 30 - 50 percent of the daily dosage given in the monographs of the single drug.  

For oral application, comminuted drug or extracts for tea.  

Note:Copious intake of fluids must be observed.  

Not longer than 14 days without the consent of a physician.  

A diuretic and mildly antispasmodic action is documented for goldenrod and Java tea.  In addition, goldenrod has an antiphlogistic effect.  Uva ursi leaf has a bacteriostatic effect in an alkaline (pH 8) urine, due to the formation of hydroquinone glucuronides and hydroquinone sulfuric acid esters from arbutin by metabolic reactions in the organism.  Pharmacological experiments for the fixed combination are not available.