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The Commission E Monographs |
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Mayapple root and resin Podophylli peltati rhizoma/resina
Podophyllumwurzelstock/Harz
Published March 13, 1986
Name of Drug
Podophylli peltati rhizoma, mayapple root, American mandrake. Podophylli peltati resina, mayapple resin, American mandrake resin.
Composition of Drug
Mayapple root consists of the dried rhizome and connected roots of Podophyllum peltatum L. [Fam. Berberidaceae].
The root contains at least 4 percent resin with podophyllotoxin. Mayapple resin consists of the resin of the dried and stored (aged) rhizome of P. peltatum L., as well as its preparations in effective dosage.
Uses
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External:
- Removal of pointed condyloma.
Contraindications
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Pregnancy.
Side Effects
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None known.
Interactions with Other Drugs
None known.
Dosage
Daily dosage:
- 1.5 - 3 g root;
- 1.5 - 3 g fluidextract ( Erg. B. 6 );
- 2.5 - 7.5 g tincture ( Erg. B. 6 );
- equivalent preparations.
Mode of Administration
Dried rhizome for production of resin exclusively for external application.
Note:The treated skin surface must not be larger than 25 cm2[approx. 10 in. x 10 in.]. Be sure to protect skin adjacent to treated area.
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