Uzara root
Uzarae radix
Uzarawurzel
Published September 1, 1990
Name of Drug
Uzarae radix, uzara root.
Composition of Drug
Uzara root consists of the dried, underground parts of 2- to 3- year-old plants of Xysmalobium undulatum (L.) R. Brown [Fam. Asclepiadaceae], as well as their preparations in effective dosage.
The drug contains glycosides with cardenolide structure.
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Uses
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Nonspecific, acute diarrhea.
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Contraindications
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Therapy with cardiac glycosides.
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Side Effects
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None known.
Interactions with Other Drugs
None known.
Dosage
Unless otherwise prescribed:
Adults:
Initial single dosage:
- preparations equivalent to 1 g herb or 75 mg total glycosides.
Daily dosage:
- equivalent to 45 - 90 mg of total glycosides, calculated as uzarin.
Mode of Administration
Ethanol-water extracts in liquid form, or as dry extracts obtained from methanol-water extractions for internal use.
Duration of Administration
If diarrhea persists for more than 3 - 4 days, consult a physician.
Actions
Inhibits intestinal motility
In high dosage, digitalis-like effects on the heart.
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