FWD 2 Botanical Adulterants Monitor

Botanical Adulterants Monitor Issue 9

Dear Reader

A review on pomegranate juice and fruit extract adulteration was published as part of the ABC-AHP-NCNPR Botanical Adulterants Program in HerbalGram 112. The paper, written by John H. Cardellina II, PhD, and Mark Blumenthal, focuses on the admixture of undeclared low-cost fruit juices, sugars, anthocyanins, and food colorants to pomegranate juice, and the spiking of pomegranate fruit extracts with pure ellagic acid from extraneous sources.


  Stefan Gafner, PhD
Chief Science Officer, ABC
Technical Director, ABC-AHP-NCNPR Botanical Adulterants Program

ABC-AHP-NCNPR Botanical Adulterants Program

Recent News 

History of Ginseng Nomenclature, Taxonomy, and Trade, and Review of Evidence for Pomegranate Adulteration Published in HerbalGram 

HerbalGram 111 coverThe ABC-AHP-NCNPR Botanical Adulterants Program has published two additional full papers in HerbalGram. Steven Foster is the author of an extensive review on the history, nomenclature, and trade of various plant species sold under the common name of “ginseng” in addition to Asian ginseng (Panax ginseng, Araliaceae) and American ginseng (Panax quinquefolius). 

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ABC-AHP-NCNPR Botanical Adulterants Program Welcomes New Supporters and Underwriters 

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Regulatory Alerts

NBTY Signs Agreement with New York Attorney General to Begin Using DNA Testing of Herbs despite No Evidence for cGMP Non-Compliance 

On September 20, 2016, Simon G. Brandler, Senior Advisor & Special Counsel to New York state Attorney General (NY AG) Eric T. Schneiderman, and Steven Cahillane, CEO of NBTY ... 

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Bosisto’s Pays Fine for Mislabeling of Tea Tree Oil Product

The Australian Competition and Consumer Commission (ACCC), an independent Commonwealth statutory authority financed by the Treasury, whose role is to enforce a range of legislations and to promote competition and fair trading in Australia ... 

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Aldi and Monde Nissin Pledge to Regularly Test Oregano Spice Products after ACCC Investigation Shows Substantial Adulteration with Olive Leaf

Based on results from a study showing adulteration of oregano (Origanum vulgare ssp. hirtum, or Origanum onites, Lamiaceae) products sold by retailers in the UK,1 the Australian consumer advocate group CHOICE verified the authenticity of a number of spice products labeled to contain oregano in Australia. 

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Upcoming Events

Below are descriptions and links to some of the upcoming conferences, seminars, and workshops that may be of interest to learn more on adulteration.

17th Annual Oxford International Conference on the Science of Botanicals (ICSB)

Oxford, MS: April 3rd - 6th, 2017

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Previous Issues of “Botanical Adulterants Monitor”

Available here.

Science Update

A UHPLC-UV/MS Method to Authenticate Grapefruit Seed Extracts

Avula B, Sagi S, Wang YH, et al. Liquid chromatography-electrospray ionization mass spectrometry analysis of limonoids and flavonoids in seeds of grapefruits, other Citrus species, and dietary supplements. Planta Med. 2016;82(11-12):1058-1069. doi: 10.1055/s-0042-107598.

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HPLC-UV Fingerprint Profile of Phenolic Compounds Helps to Distinguish Black Cohosh from Asian Actaea species

Bittner M, Schenk R, Springer A, Melzig MF. Economical, plain, and rapid authentication of Actaea racemosa L. (syn. Cimicifuga racemosa, black cohosh) herbal raw material by resilient RP-PDA-HPLC and chemometric analysis. Phytochem Anal. 2016;27(6):318-325.

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Investigation into the Quality of Rhodiola spp. Raw Materials Using 1H NMR and HPTLC

Booker A, Zhai L, Gkouva C, Li S, Heinrich M. From traditional resource to global commodities:–A comparison of Rhodiola species using NMR spectroscopy–metabolomics and HPTLC. Front Pharmacol. 2016;7:254. doi: 10.3389/fphar.2016.00254.

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Next-Generation More Successful than Sanger Sequencing in DNA Identification of Herbal Raw Materials

Ivanova NV, Kuzmina ML, Braukmann TW, Borisenko AV, Zakharov EV. Authentication of herbal supplements using next-generation sequencing. PLoS One. 2016;11(5):e0156426. doi: 10.1371/journal.pone.0156426.

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DNA Barcoding for the Identification of Medicinal and Culinary Mushrooms

Reviewed: Raja HA, Baker TR, Little JG, Oberlies NH. DNA barcoding for identification of consumer-relevant mushrooms: A partial solution for product certification? Food Chem. 2017;214:383-392.


Assessment of the Identity of Raw Material Samples Sold in Indian Markets as Asoka

Santhosh Kumar JU, Gogna N, Newmaster SG, et al. DNA barcoding and NMR spectroscopy-based assessment of species adulteration in the raw herbal trade of Saraca asoca (Roxb.) Willd, an important medicinal plant. Int J Legal Med. 2016;130(6):1457-1470.

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Useful Links and Resources

For more information and updates on the work of the three partner organizations of the ABC-AHP-NCNPR Botanical Adulterants Program, please visit ABC at www.herbalgram.org, AHP at www.herbal-ahp.org, and NCNPR at www.pharmacy.olemiss.edu/ncnpr.

Other Helpful Resources and Links

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About the

The ABC-AHP-NCNPR Botanical Adulterants Program is a consortium of independent nonprofit organizations whose mission relates to education, scientific research, and quality of botanical dietary ingredients and related plant-derived materials. The consortium is headed by three nonprofit groups dealing with education and research on medicinal herbs and other beneficial plants: the American Botanical Council, the American Herbal Pharmacopoeia, and the National Center for Natural Products Research at the University of Mississippi. The program is underwritten or endorsed by more than 130 natural products industry companies, independent analytical laboratories, contract research organizations, nonprofit and professional organizations, trade associations, accredited institutions of education in natural medicine, law firms, and media companies that are involved in the production, supply, manufacture, distribution, marketing, analysis, research, and/or education of herbal dietary ingredients and supplements, in the United States and internationally. All publications of the Program are available free-access on its homepage including the “Botanical Adulterants Monitor,” an e-newsletter that conveys Program news, regulatory updates, and recent scientific publications related to adulteration, contamination, identity, and authenticity of botanical raw materials, extracts, and essential oils. Companies, organizations, foundations, and/or individuals interested in supporting this program are invited to contact Ms. Denise Meikel, ABC Development Director, at (512) 926-4900, ext. 120, or by email.


Thank You to Our Supporters

Underwriters and Supporters of the ABC-AHP-NCNPR Botanical Adulterants Program (as of Dec 14, 2016)*

*By acknowledging the generous support of these companies and organizations, ABC, AHP, and NCNPR are not endorsing any ingredients or products that may be produced or marketed by them

Financial Underwriters

21st Century Healthcare

AdvoCare International L.P.

Agilent Technologies, Inc.

Aloecorp, Inc.

Amen Clinics

Amway/Nutrilite Health Institute

Artemis International, Inc.

Atrium Innovations

Aveda Corporation

Beachbody, LLC

BI Nutraceuticals


Bionorica SE


Botanical Liaisons

Bruker BioSpin


Cepham, Inc.

Chemi Nutra

CNCA Health

Complete Phytochemical Solutions

Crila Health

dicentra, Inc.

Doctor’s Best

Dr. Bronner's Magic Soaps

DolCas Biotech, LLC

Douglas Laboratories

Draco Natural Products

Emerson Ecologics

Enzymatic Therapy, Inc.

Ethical Naturals, Inc.

Eu Yan Sang International




Flavex Naturextrakte GmbH


Fruit d'Or

Gaia Herbs

GE Nutrients, Inc.

Global Health Industries

GNC, Inc.

Healthy Lifestyle Brands, LLC

Helios Corp.

Herb Pharm

Herbalife International, Inc.

Horphag Research


Indena USA, Inc.

Indfrag Limited

Ingredient Identity

Ixoreal Biomed, Inc.

Jarrow Formulas

Layn USA, Inc.


Markan Global Enterprises, Inc.

Martin Bauer, Inc.

MediHerb / Integria Healthcare

Metagenics, Inc.

Natreon, Inc.

Natural Alternatives International, Inc.

Natural Factors Nutritional Products, Inc.
   /Bioclinic Naturals 
Financial Underwriters

Natural Grocers by Vitamin Cottage

Natural Remedies Pvt. Ltd.

Nature's Sunshine Products

Nature's Way


Naturex, Inc.

NBTY, Inc.

New Chapter, Inc.

The New Frontier Foundation Fund of the Greater Cedar Rapids Community Foundation

Ningbo Greenhealth Pharmaceutical Co., Ltd.

Novel Ingredients

NOW Foods

Nu Skin Enterprises/Pharmanex

Nutraceuticals Corp.

Organic India

Ortho Molecular Products

Pacific Nutritional Inc.

Paragon Laboratories

Pathway International Pty Limited

Perrigo Company

Pharmatoka SAS

Pharmavite, LLC

Phoenix Formulations

PLT Health Solutions, Inc.

Polyphenolics, Division of Constellation Brands, Inc.

Pure Encapsulations

Rainbow Light Nutritional Systems

RFI Ingredients, LLC

Rosenbush and Zimmerman Family Fund

Sabinsa Corporation

Schwabe North America


Shaklee Corp.

Standard Process, Inc.

Strategic Sourcing, Inc.

Thorne Research, Inc.

Traditional Medicinals, Inc.

TSI Group


Univera, Inc.

Valensa International

V.D.F. FutureCeuticals

Verdure Sciences

Vitamin Shoppe

VitaQuest International

Whole Foods Market

Trade Associations

American Herbal Products Association (US)

Australian Self Medication Industry (Australia)

Australian Tea Tree Industry Association (Australia)

British Herbal Medicine Association (UK)

Canadian Health Food Association (Canada)

Complementary Medicines Australia (Australia)

Consumer Healthcare Products Association (US)

Council for Responsible Nutrition (US)

International Alliance of Dietary/Food Supplement Associations (IADSA)

National Animal Supplement Council (US)

Natural Products Association (US)

Natural Products New Zealand (NZ)

United Natural Products Alliance (US)

Nonprofit/Professional Associations

Academy of Integrative Health & Medicine

American Association of Naturopathic Physicians

American Herbalists Guild

American Society of Pharmacognosy

AOAC International

Council of Colleges of Acupuncture and Oriental Medicine

Homeopathic Pharmacopoeia Convention of the United States
Integrative Healthcare Policy Consortium

Irish Register of Herbalists (IRE)

National Institute of Medical Herbalists (UK)

Natural Health Products Research Society of Canada (NHPRS Canada)

Personalized Lifestyle Medicine Institute

Society for Medicinal Plant and Natural Product Research (GA)


Bastyr University

Boucher Institute for Naturopathic Medicine

Center for Natural Products Technologies, College of Pharmacy, University of Illinois-Chicago

Hong Kong Baptist University’s School of Chinese Medicine

National College of Natural Medicine

Southwest College of Naturopathic Medicine

University of Bridgeport College of Naturopathic Medicine
Third-Party Analytical Laboratories

Alkemist Labs

AuthenTechnologies LLC

Bent Creek Institute

BotaniCert (France)

British Columbia Institute of Technology


Covance Laboratories

Creative Accord, LLC

Eurofins Scientific Inc.

Flora Research Labs

NSF International

PhytoLab (Germany)

Spectrix Labs

Tampa Bay Analytical


Alive Publishing Group

Delicious Living


Holistic Primary Care

Informa Exhibitions US

Integrator Blog

Media Relations, Inc.

Modern Healthcare Practitioner

Natural Foods Merchandiser

Natural Medicine Journal

Natural Products INSIDER


Nutraceuticals World


Nutrition Business Journal

Nutrition Industry Executive

Nutritional Outlook

Vitamin Retailer

WholeFoods Magazine


Law Firms & Regulatory Consultants

Amin Talati & Upadhye, LLC

Greenberg Traurig, LLP (James Prochnow)

Law Office of Holly Bayne, P.C.

Robert Forbes & Associates

Susan Brienza, LLC

Ullman, Shapiro & Ullman, LLP

Contract Research Organizations

KGK Synergize


Research Institutes

Korean Ginseng Research Institute

Shanghai Research Center for TCM Modernization/Shanghai Institute of Materia Medica of the Chinese Academy of Sciences


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